Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)

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Analysis of toxic constituents of Nerium oleander by GC-MS-MS

Authors
Surabhi Sharma1, *, Karan Sharma1
1Jaipur National University, Jaipur, Rajasthan, India
*Corresponding author. Email: surabhi.sharma@jnujaipur.com
Corresponding Author
Surabhi Sharma
Available Online 29 December 2025.
DOI
10.2991/978-94-6463-976-6_2How to use a DOI?
Keywords
Phytochemical; Nerium oleander; Toxicological; Metabolites; GC-MS MS
Abstract

Cardiac Glycosides along with other bioactive compounds are found in Nerium oleander, which is a plant used in India for its ornamental values. The study presented here classify and identifies the elements toxic in nature in this plant by using GC-MS MS. In this study fresh leaves were taken and were dried in shade, pulverised and were further taken for solvent extraction with pet ether and diethyl ether. The extract left was then taken further for its analysis using GC-MS MS to attain the mass of its chemical components. To make our study we took the plants from various sited of two cities i.e. Jhansi and Delhi to check the difference in both the samples in terms of their toxicity. During the analysis many toxic components like digitoxigenin, neriifolin with other metabolites like terpenoids, phytosterols were seen. The presence of these toxins made the plant a potent cardiac and neuro-toxic plant. With the help of this study we found the toxicity in the plant with GC-MS MS as it is a consistent tool for quantification and etection of any toxic components present. This study will help in toxicological sketching and identification of poison in forensic analysis of any poisoning cases related with Nerium oleander.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)
Series
Advances in Intelligent Systems Research
Publication Date
29 December 2025
ISBN
978-94-6463-976-6
ISSN
1951-6851
DOI
10.2991/978-94-6463-976-6_2How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Surabhi Sharma
AU  - Karan Sharma
PY  - 2025
DA  - 2025/12/29
TI  - Analysis of toxic constituents of Nerium oleander by GC-MS-MS
BT  - Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)
PB  - Atlantis Press
SP  - 4
EP  - 26
SN  - 1951-6851
UR  - https://doi.org/10.2991/978-94-6463-976-6_2
DO  - 10.2991/978-94-6463-976-6_2
ID  - Sharma2025
ER  -