Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)

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In-silico analysis of the phytochemicals in the extracts of seeds from Michelia champaca L

Authors
Keerthi S. Kotabal1, Yashwanth Kh1, Preeti S. Kotabal1, S Vijaya Kumari1, G Dhanalakshmi1, Sharad S. Achar2, *
1Padmashree Institute of Management and Sciences, Tavarekere – Kengeri main road, Kommaghatta, Bengaluru, 560060, India
2Dayananda Sagar College of Engineering, Autonomous Institute, Affiliated to Visveswaraya Technological University, Shavige Malleshwara Hills, Kumaraswamy Layout, Bengaluru, 560111, India
*Corresponding author. Email: sharad-bt@dayanandasagar.edu
Corresponding Author
Sharad S. Achar
Available Online 29 December 2025.
DOI
10.2991/978-94-6463-976-6_9How to use a DOI?
Keywords
Michelia champaca L; ADME; Phytochemical
Abstract

In the traditional system of medicines, plants are the primary source for treatment of various ailments. This study focuses on the possibility of the health benefits of seeds from Michelia champaca L. The seeds were subjected to qualitative and quantitative tests and observed to contain a wide range of phytochemicals. The extracts were obtained by maceration and qualitative and quantitative tests were performed. These tests revealed the presence of six phytochemicals. Further, the identification and validation of these phytochemicals from the seeds of Michelia champaka L. was carried out by using in-silico techniques. This was initiated by using SwissADME and Toxtree softwares. The SwissADME software predicted dodecanoic acid, 1-methylethyl ester as a more potent phytochemical as it satisfied several crucial parameters of lead likeliness. Whereas analysis from the Toxtree software, four compounds i.e. hexadecanoic acid methyl ester, 12,15- octadecadienoic acid, methyl ester dodecanoic acid 1- methylethyl ester, 7,10 octadecadienoic acid methyl ester was predicted to be less toxic. The presence of chemical compounds in the seeds contributes to their medicinal properties, offering insight into the interaction between various bioactive components and the human body. This study highlights the need to reconsider the potential of Michelia champaca L. seeds, as they are a valuable source of bioactive compounds with significant potential for drug development and nutritional improvement. Consequently, the findings underscore the pharmacological promise of Michelia champaca L. and emphasize the importance of exploring underutilized natural resources for their potential health benefits in functional foods and medicine.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)
Series
Advances in Intelligent Systems Research
Publication Date
29 December 2025
ISBN
978-94-6463-976-6
ISSN
1951-6851
DOI
10.2991/978-94-6463-976-6_9How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Keerthi S. Kotabal
AU  - Yashwanth Kh
AU  - Preeti S. Kotabal
AU  - S Vijaya Kumari
AU  - G Dhanalakshmi
AU  - Sharad S. Achar
PY  - 2025
DA  - 2025/12/29
TI  - In-silico analysis of the phytochemicals in the extracts of seeds from Michelia champaca L
BT  - Proceedings of the International Conference on Intelligent Information Systems Design and Indian Knowledge System Applications (ICISDIKSA 2026)
PB  - Atlantis Press
SP  - 133
EP  - 141
SN  - 1951-6851
UR  - https://doi.org/10.2991/978-94-6463-976-6_9
DO  - 10.2991/978-94-6463-976-6_9
ID  - Kotabal2025
ER  -