Proceedings of the International Conference on Sustainable Innovation with Artificial Intelligence and Machine Learning 2025 (ICSIAIML 2025)

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Green In Situ Self-Assembling Nanoparticles within Waterless Granules for Oncology Applications

Authors
Gayatri Sharma1, Nishita Burade1, Sunitha Sampathi1, Nitiraj V. Kulkarni1, Jagadish V. Tawade1, *
1Vishwakarma University, Pune-411048, Maharashtra, India
*Corresponding author. Email: Jagadish.tawade@vupune.ac.in
Corresponding Author
Jagadish V. Tawade
Available Online 6 January 2026.
DOI
10.2991/978-94-6463-948-3_43How to use a DOI?
Keywords
Waterless-granules; In situ self-assembly nanoparticles (ISSANPs); Solvent free nanomedicines; Tumor targeted drug delivery
Abstract

The combination of nanotechnology with eco-friendly drug design has led to innovative cancer treatment therapies. Water-less granules encapsulated in situ self-assembling nanoparticles (ISSANPs) offer a sustainable method of administering chemotherapeutics that are poorly soluble in water, improving bioavailability and therapeutic effectiveness while reducing pharmaceutical waste. These granules interact with biological fluids during administration, which causes nanoparticles to self-assemble (SA) for more precise tumor deliver with less systemic toxicity. This review discusses the various formulation excipients, assembly triggers and physiological factors influencing self-assembly. Advantages of using this technique include improved stability, elimination of organic solvent, enhanced permeability and retention (EPR) for passive and active tumor targeting, and potential for better patient compliances. Overall, this review combine nanotechnology, Eco-friendly and controlled drug release, and using these the various evaluations offering a suitable alternative to conventional cancer treatments.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Sustainable Innovation with Artificial Intelligence and Machine Learning 2025 (ICSIAIML 2025)
Series
Advances in Intelligent Systems Research
Publication Date
6 January 2026
ISBN
978-94-6463-948-3
ISSN
1951-6851
DOI
10.2991/978-94-6463-948-3_43How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Gayatri Sharma
AU  - Nishita Burade
AU  - Sunitha Sampathi
AU  - Nitiraj V. Kulkarni
AU  - Jagadish V. Tawade
PY  - 2026
DA  - 2026/01/06
TI  - Green In Situ Self-Assembling Nanoparticles within Waterless Granules for Oncology Applications
BT  - Proceedings of the International Conference on Sustainable Innovation with Artificial Intelligence and Machine Learning 2025 (ICSIAIML 2025)
PB  - Atlantis Press
SP  - 616
EP  - 625
SN  - 1951-6851
UR  - https://doi.org/10.2991/978-94-6463-948-3_43
DO  - 10.2991/978-94-6463-948-3_43
ID  - Sharma2026
ER  -