FTIR Characterization of Elaeis guineensis and Centella asiatica Extracts and Preliminary Spreadability Assessment for Gel Development

DOI

10.2991/978-94-6239-836-8_9How to use a DOI?

Keywords

Elaeis guineensis; Centella asiatica; FTIR; phytochemical screening; spreadability; preformulation; botanical extracts

Abstract

Chronic wounds motivate the development of topical systems containing plant-derived constituents with potential relevance to tissue repair. This descriptive preformulation study characterized Elaeis guineensis and Centella asiatica leaf extracts by qualitative phytochemical screening and individual Fourier-transform infrared (FTIR) spectroscopy and summarized preliminary spreadability observations from three formulation variations. Both extracts tested positive for alkaloids, flavonoids, saponins, tannins, and steroids, whereas terpenoids were negative under the applied Liebermann-Burchard test. The individual FTIR spectra showed bands in the O-H, aliphatic C-H, carbonyl/aromatic, and fingerprint regions. Because spectra of the physical mixture, excipients, and final combined gel were not available, the present data do not establish extract-extract or extract-gel compatibility or formulation stability. The three formulation variations produced descriptive mean spread diameters of 5.02, 5.57, and 5.28 cm for variations 0.10, 0.05, and 0.025, respectively. However, D1 and D2 were perpendicular dimensions from a single spread event rather than independent replicates; therefore, the values cannot support formulation ranking or inferential comparison. These findings provide baseline characterization for future formulation work. Confirmatory studies should fully define botanical and formulation procedures, use reproducible FTIR acquisition, analyze the physical mixture and final gel, and perform independently replicated physicochemical and stability testing.

Copyright

© 2026 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - S. Lysa Yolanda Anggraini
AU  - Humairah Medina Liza Lubis
PY  - 2026
DA  - 2026/11/11
TI  - FTIR Characterization of Elaeis guineensis and Centella asiatica Extracts and Preliminary Spreadability Assessment for Gel Development
BT  - Proceedings of the3rd Malikussaleh International Conference on Health and Disaster Medicine 2026  (MICOHEDMED 2026)
PB  - Atlantis Press
SP  - 82
EP  - 90
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6239-836-8_9
DO  - 10.2991/978-94-6239-836-8_9
ID  - Anggraini2026
ER  -