Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)

A Rare Case of Dorsolumbar Pott’s Spine with Spinal Cord Compression and Lymphadenopathy

Authors
K. R. V. S. Hymavathi1, *, S. Venkatesh1, Thanati Joel Nathan1, B. Indrani1, P. Vyshnavi1, M. Meghanaa2, Shaik Ameena3
1Department of Pharmacology and Pharmacy Practice, Nirmala College of Pharmacy, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, India
2Apollo Hospitals, Hyderabad, Telangana, India
3Manipal Hospitals, Tadepalli, Guntur, Andhra Pradesh, India
*Corresponding author. Email: ranihymavathikota@gmail.com
Corresponding Author
K. R. V. S. Hymavathi
Available Online 13 August 2025.
DOI
10.2991/978-94-6463-813-4_21How to use a DOI?
Keywords
Dorsolumbar Region; Lymph Adenopathy; Cord Compression; Anti-Tubercular Therapy
Abstract

The dorsolumbar region is the primarily affected deformity in Pott’s spine, gradually progressing to vertebral destruction, spinal canal narrowing, and neurological impairments. Considering, it as an extrapulmonary infection Mycobacterium tuberculosis has a very uncommon and low incidence of < 1% of all TB cases in India. Early diagnosis and management place a pivotal role in preventing its complications. A 43-year-old female presented with progressive back pain, fever, weight loss, and difficulty in walking. On examination, tenderness was observed over the dorsolumbar region with mild kyphotic deformity. MRI features suggested a decrease in vertebral height with sclerosis in the D12 and L1 vertebrae and marrow edema. D12-L1 range has shown spinal cord narrowing with significant cord compression and edema. The para-aortic lymphnodes were enlarged and there is an absence of collections in pre-vertebral, para-vertebral, or epidural spaces. Based on these evidences the diagnosis was found to be Pott’s spine (spinal tuberculosis). The ATT (Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol) stands as the first line for the patient with a duration of 12 months. The patient underwent surgical decompression along with stabilization for spinal instability and cord compression. This case report highlights the challenges in managing TB along with uncontrolled DM. The most novel findings included in this case was the absence of paravertebral abscess which is considered almost uncommon in overall spinal TB cases.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)
Series
Advances in Health Sciences Research
Publication Date
13 August 2025
ISBN
978-94-6463-813-4
ISSN
2468-5739
DOI
10.2991/978-94-6463-813-4_21How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - K. R. V. S. Hymavathi
AU  - S. Venkatesh
AU  - Thanati Joel Nathan
AU  - B. Indrani
AU  - P. Vyshnavi
AU  - M. Meghanaa
AU  - Shaik Ameena
PY  - 2025
DA  - 2025/08/13
TI  - A Rare Case of Dorsolumbar Pott’s Spine with Spinal Cord Compression and Lymphadenopathy
BT  - Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)
PB  - Atlantis Press
SP  - 282
EP  - 289
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-813-4_21
DO  - 10.2991/978-94-6463-813-4_21
ID  - Hymavathi2025
ER  -