Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)

Evaluating Threat Parameters Associated with Antibiotic Resistance and Susceptibility Patients with Urinary Tract Infections

Authors
Jyothirlekha Adari1, *, Katta Bhargavi1, Aayesha Ata1, M. S. R. Bapiraju1, Shaik Faizan Ali2, Pulagam Madhubabu3
1Department of Pharmacy Practice, Shri Vishnu College of Pharmacy, Bhimavaram, West Godavari, Andhra Pradesh, India
2Department of Pharmacology and Pharmacy Practice, Nirmala College of Pharmacy, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, India
3Omics Next Gen Laboratories, Bhimavaram, West Godavari, Andhra Pradesh, India
*Corresponding author. Email: jyothirlekha.5376@gmail.com
Corresponding Author
Jyothirlekha Adari
Available Online 13 August 2025.
DOI
10.2991/978-94-6463-813-4_32How to use a DOI?
Keywords
Urinary Tract Infections; Resistance; Susceptibility; Empirical Therapy
Abstract

A significant public health issue, urinary tract infections (UTIs) is more common in women (59%) than in men. E. coli is the most commonly isolated pathogen (52%), with K. pneumoniae and Staphylococcus following closely behind. According to our research, Gram-positive bacteria are resistant to trimethoprim, penicillin, nitrofurantoin, and doxycycline, but Gram-negative pathogens are very resistant to ampicillin, cefepime, norfloxacin, and trimethoprim. Amikacin, nitrofurantoin, and ciprofloxacin are susceptible to Gram-negative bacteria, whereas amikacin and piperacillin-tazobactam are more susceptible to Gram-positive organisms. Antibiotic resistance is largely caused by risk factors like smoking, drinking alcohol, and eating non-vegetarian food frequently. In order to properly treat medication resistance, empirical therapy is advised.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)
Series
Advances in Health Sciences Research
Publication Date
13 August 2025
ISBN
978-94-6463-813-4
ISSN
2468-5739
DOI
10.2991/978-94-6463-813-4_32How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Jyothirlekha Adari
AU  - Katta Bhargavi
AU  - Aayesha Ata
AU  - M. S. R. Bapiraju
AU  - Shaik Faizan Ali
AU  - Pulagam Madhubabu
PY  - 2025
DA  - 2025/08/13
TI  - Evaluating Threat Parameters Associated with Antibiotic Resistance and Susceptibility Patients with Urinary Tract Infections
BT  - Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)
PB  - Atlantis Press
SP  - 417
EP  - 440
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-813-4_32
DO  - 10.2991/978-94-6463-813-4_32
ID  - Adari2025
ER  -