Advances in Health Sciences Research
4317 articles
Proceedings Article
Production and Characterization of Human Insulin Precursor in Pichia Pastoris X-33
Dudi Hardianto, Efrida Martius, Fahroziah Assyifa, Dihan Laziba, Uli J. Nasution, Fransiska C. Sekaringtyas, Juwartina I. Royani
The prevalence of Insulin Dependent Diabetes Mellitus (IDDM) has increased significantly in the last decades, resulting in an increased demand for insulin. In addition, new routes of oral and inhaled insulin require higher doses thus increasing insulin requirements. Insulin is the primary drug in patients...
Proceedings Article
Effect of Sterilization on Protein Adsorption of Micro- and Nano-sized Aluminum Hydroxide Adjuvant
Damai Ria Setyawati, Sjaikhurrizal El Muttaqien, Donny Ramadhan, Etik Mardliyati
Aluminum hydroxide (AH) is one of the aluminum-based adjuvants that forms needle-like crystalline structure with the average particle size of 1–20 µm. Due to their favorable safety profile, AH adjuvant has been used widely in various human vaccine in diphtheria, tetanus, pertussis, hepatitis, and papilloma...
Proceedings Article
Cloning and Expression of HBcAg Using Food Grade Vector pNZ8149 in Lactococcus Lactis for the Development of HBV Therapeutic Vaccine
Rifqiyah N. Umami, Rahma I. Anwar, Hidayah Murtiyaningsih, Apon Z. Mustopa
Hepatitis B virus (HBV) infection remains a major cause of chronic liver diseases which may develop into cirrhosis and hepatocellular carcinoma (HCC). Although HBV prophylactic vaccine is available, currently there is no complete cure for chronic hepatitis B (CHB). One of the alternatives for CHB treatment...
Proceedings Article
Molecular Detection of Eimeria Zuernii in Cattle in Malang, East Java, Indonesia by Nested-PCR
Fitrine Ekawasti, April H. Wardhana, Farlin Nepho, Eko S. Purwanto, Dyah H. Sawitri, Eny Martindah
Coccidiosis continues to be one of the most important issues in animal health and generates significant economic losses to the livestock industry in Indonesia, specifically due to Eimeria spp. Infections. Eimeria are specific to a particular host Eimeria and multi-species infections are more prevalent...
Proceedings Article
Genetic Variation of the Causal Agent of Sheep-Associated Malignant Catarrhal Fever in Buffalo in Indonesia: Using a Repeat-Sequence Polymerase Chain Reaction
Agus Wiyono, Muharam Saepulloh, Rini Damayanti
A study on the genetic variation of Ovine Herpesvirus-2 (OVH-2), the causal agent of sheep-associated malignant catarrhal fever (SA-MCF), in buffalo in Indonesia using a repeat-sequence polymerase chain reaction (RS-PCR) has been conducted. Samples of heparinized blood and/or pre-scapular or pre-femoral...
Proceedings Article
Artemisinin and Artemisia Annua Leaf Ether Extract for the Treatment of Coccidosis in Chicken
April H. Wardhana, Ening Wiedosari
The widespread occurrence of coccidiostat resistance in chicken farms has prompted the search for alternatives to treat coccidiosis caused by Eimeria tenella. This study aimed to compare the efficacy of standard artemisinin and Artemisia annua (A. annua) leaf ether extract when administered at 3–2–3...
Proceedings Article
Evaluation of Gamal Leaves (Gliricidia Sepium) as Anthelmintic Forages Against Gastrointestinal Nematodes in Sheep
Dyah H. Sawitri, April H. Wardhana, Farlin Nefho, Eko Setyo Purwanto, Eny Martindah, Wisri Puastuti
Several studies have demonstrated that ruminant-fed forages containing bioactive anthelmintics (tannins, alkaloids, and flavonoids) can be used to suppress nematode worms. The objective of this study was to examine any potential direct anthelmintic effects of G.sepium leaves containing Plant Secondary...
Proceedings Article
The Utilization of Chitosan in Streptococcus Agalactiae Encapsulation as Mastitis Vaccine Carrier Candidate
Dadang Priyoatmojo, Tri Handayani, Afi C. Trinugraha, Teguh Wahyono, Ade L. Yunus, Abdi W. Septama
Mastitis is a disease in dairy cattle that causes economic losses to farmers around the world. Mastitis is caused by microbes with Streptococcus agalactiae being the main cause of subclinical mastitis. The prevention and control of mastitis is through sanitation management, drug administration and vaccination...
Proceedings Article
The Prevalence of Soil Transmitted Helminth Among Elementary School Students in Buton, Province of South Sulawesi
R. A. Wigati, Dicky Andiarsa, Nurhidayati Nurhidayati, Tri Ramadhani, Yusnita M. Anggraini
Soil Transmitted Helminth (STH) is a common global helminth infection. Children have a high risk of infection with STH. Indonesia is particularly vulnerable to STH infections due to ideal environmental and socioeconomic conditions in many areas. Nearly, 200 million people across 31 provinces are estimated...
Proceedings Article
Seroprevalence of Japanese Encephalitis Virus in Pigs and Cattle: An Evaluation from Tangerang Regency
Muhammad U. Riandi, Mara Ipa, Tri Wahono, Joni Hendri, Subangkit, Triwibowo A. Garjito
Japanese encephalitis (JE) is a zoonotic vector-borne disease in humans and animals in the Asia Pacific. This RNA virus is transmitted to humans through mosquito bites from viral amplifiers, such as pigs, poultry, bats, and other vertebrates. In the spread of JEV, herons are considered the reservoir,...
Proceedings Article
Determinants of Community Distrust of Drugs Deliverers in the Catchment Areas of Waihaong and Air Salobar Health Centers, Ambon
Ezra P. A. Siwtiory, Christiana R. Titaley, Nathalie E. Kailola, Yuniasih M. J. Taihuttu, Bertha J. Que, Chrisia J. Kakisina, Cindy Kamarmir, Alison Krentel
Lymphatic Filariasis (LF) is a chronic infectious disease caused by worms from the nematode group. Mass drug administration (MDA) for LF is carried out in endemic communities to eliminate lymphatic filariasis. Previous analysis shows that one of the factors associated with community compliance with taking...
Proceedings Article
Update on Human Schistosomiasis Prevalence and Schistosomiasis Control Intervention in Poso Regency, Central Sulawesi Province, Indonesia
Anis N. Widayati, Opyn Mananta
Schistosomiasis in Indonesia is caused by the trematode worm, Schistosoma japonicum, with the snail Oncomelania hupensis lindoensis as its intermediate host. In Indonesia, it spreads in three endemic areas only: Napu and Bada Highlands of Poso Regency and Lindu Highland of Sigi Regency, Sulawesi Tengah...
Proceedings Article
Detection of Leptospira Bacteria in Rats in Ciomas Sub-district, Bogor District, West Jawa Using Real-Time PCR Method
Gunawan Gunawan, Hanny Zamsiar, Agus A. Wibowo, Yahidin Selian, Dessy L. Utami
Leptospirosis is a zoonotic disease caused by bacteria from the genus Leptospira. Leptospira bacteria can infect rats, dogs, cats, raccoons, cattle, horses, and other mammals. The main reservoir of leptospirosis in Indonesia is rats. Indonesia is a country with a high risk of developing leptospirosis,...
Proceedings Article
Infestation of Leptospira in Rodents at the Perimeter Area in “Pelabuhan Ratu” Port, Sukabumi District
Marliah Santi, Endang P. Astuti, Yuneu Yuliasih, Mutiara Widawati
Leptospirosis is a neglected zoonotic disease with global health implications. A significant impact of Leptospirosis happens in tropical regions, including Indonesia. Rodents play an essential role in the spread of Leptospirosis due to their rapid population growth and proximity to humans. This study...
Proceedings Article
Avian Influenza Virus Endemicity During the Covid-19 Pandemic in Indonesia
N. L. P. I. Dharmayanti, Diana Nurjanah, Teguh Suyatno, Harimurti Nuradji, Suraida Meisari, Risa Indriani
The covid-19 pandemic that occurred in the beginning of 2020 has affected all sectors, particularly in health and economic sectors. The Avian Influenza Virus (AIV), a zoonotic virus that have been reported endemic in Indonesia since 2003, might be affected by this condition. There is very limited information...
Corrigendum
Correction to: Youth Imagination About Being an Indonesian
Sartana, Edilburga Wulan Saptandari, Avin Fadilla Helmi
Corrigendum
Correction to: Food Away From Home: The Characteristics of Socio-Demographics Among Office Workers in Jakarta During the Covid-19 Pandemic
Ayu Kristiningrum, Helda Khusun, Dian Novita Chandra