Proceedings of the Conference on Bioengineering for Global Health (SYMRESEARCH 2.0 2025)

Conference on Bioengineering for Global Health (SYMRESEARCH 2.0 2025)

📍Pune, India🗓️ 18-20 September 2025

Ensuring Implant Longevity: Shelf-Life Assessment of Nanocoated Titanium Surface

Authors
Laxmi Jadhav1, 2, Vaibhav Madiwal1, 2, Jyutika Rajwade1, 2, *
1Nanobioscience Group, Agharkar Research Institute, G.G Agarkar Road, Pune, 411 004, India
2Savitribai Phule Pune University, Homi Bhabha Road, Pune, 411007, India
*Corresponding author. Email: jrajwade@aripune.org
Corresponding Author
Jyutika Rajwade
Available Online 31 August 2026.
DOI
10.2991/978-94-6239-756-9_3How to use a DOI?
Keywords
Surface modifications; accelerated aging; shelf life
Abstract

Titanium dental implants are often modified for enhanced osseointegration and antibacterial activity using techniques like sandblasting, acid etching, anodization or antibacterial coatings. However, these modified surfaces are highly reactive and hence prone to contamination during storage which may decrease their bioactivity. Therefore, evaluating the long-term shelf-life stability of modified implants is a critical step before clinical translation. In the present study we report the shelf-life assessment of titanium implants modified with nano coatings of Silver (Ag) and Cobalt (Co) using DC Sputtering. The coated discs were stored in oxygen and nitrogen-purged sealed bottles for 33 days at 60℃, simulating one year of storage at 25℃ (ASTM F1980-16 method). Following storage, biocompatibility was evaluated using MG-63 osteoblast cells while antibacterial activity was assessed against Streptococcus sanguinis and Aggregatibacter actinomycetemcomitans using a modified JIS Z 2801 method. Both surfaces after accelerated aging retained 100% of their antibacterial activity along with cell viability and attachment. Among the two, Ti-Co displayed maximum cell spreading as compared to Ti-Ag surfaces. This is one of the first studies to demonstrate long-term shelf-life stability of Ag and Co modified titanium implants, addressing an often-overlooked aspect viz., performance after storage. Further studies on in vivo compatibility are warranted to further validate their long-term biocompatibility and clinical translation.

Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the Conference on Bioengineering for Global Health (SYMRESEARCH 2.0 2025)
Series
Advances in Biological Sciences Research
Publication Date
31 August 2026
ISBN
978-94-6239-756-9
ISSN
2468-5747
DOI
10.2991/978-94-6239-756-9_3How to use a DOI?
Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Laxmi Jadhav
AU  - Vaibhav Madiwal
AU  - Jyutika Rajwade
PY  - 2026
DA  - 2026/08/31
TI  - Ensuring Implant Longevity: Shelf-Life Assessment of Nanocoated Titanium Surface
BT  - Proceedings of the Conference on Bioengineering for Global Health (SYMRESEARCH 2.0 2025)
PB  - Atlantis Press
SP  - 21
EP  - 32
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6239-756-9_3
DO  - 10.2991/978-94-6239-756-9_3
ID  - Jadhav2026
ER  -