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Endothelial dysfunction, as assessed by laser-Doppler flowmetry (LDF) is an accepted method to measure microvascular reactivity, which correlates with cardiovascular risk factors in several patient populations. The aim of our prospective cohort study was to assess determinants of LDF parameters and to...

Introduction: The feasibility of measuring the diastolic pressure-decay constant (tau) in normal and hypertensive humans is not established and the clinical and physiological relevance of tau is not known. Methods: Studies were performed in the non-invasive cardiac laboratory in subjects who had been...

Objectives: Evidence points towards a grading effect of the severity of ED in the predictive ability of this condition for CV events and all-cause mortality. We conducted a meta-analysis of all longitudinal studies for investigating the role of severity of ED in predicting risk of clinical events. Methods:...

The contemporary world is becoming very stressful due to the fast changing Information and Communication Technology (ICT). Academic Institutions are also heavily depending on technology for teaching, learning and research. Therefore the pressures of ICT use in academics create technostress among academicians....

Since the last few decades, constructing flexible parametric classes of probability distributions has been the most popular approach in the Bayesian analysis. As compared to simple probability models, a mixture model of some suitable lifetime distributions may be more capable of capturing the heterogeneity...

Appropriate restrictions of Lax operators which allows to construction of (2+1dimensional integrable field systems, coming from centrally extended algebra of pseuddifferential operators, are reviewed. The gauge transformation and the reciprocal link between three classes of Lax hierarchies are established.

Transformations of coordinates of points in an infinite-dimensional graded vector space, the so-called contact transformations, are examined. An infinite jet prolongation of the extended configuration space of N spinless particles is the subspace of this vector space. The dynamical equivalence among...

Anisotropic phenomena can be observed almost everywhere in nature. This makes them important sub jects for theoretical and experimental studies. In this work, we focus on the study of anisotropic quasi-self-similar signals. It holds that the classical multifractal formalism in all its formulations does...

Hepatitis B virus (HBV) remains a leading cause of chronic hepatitis, maternal complications, and neonatal deaths in sub-Saharan Africa. Pregnant women serve as a major reservoir for the persistence and ongoing transmission of hepatitis B virus and HIV in a generalized heterosexual epidemic. The aim...

Background: Cancer continues to rise as a contributor to premature death in the developing world. Despite this, little is known about whether cancer outcomes are related to a country’s income level, and what aspects of national healthcare systems are associated with improved cancer outcomes. Methods:...

Background: Modest elevations in plasma low-density lipoprotein (LDL)-cholesterol have been shown to confer a significant increase in cardiovascular risk. Endothelin (ET)-1 is a vasoconstrictor peptide with proatherogenic properties. The experimental aim of this study was to determine whether ET-1 system...

Introduction: Inflammatory state is activated in metabolic syndrome and may explain part of the adverse prognosis of this entity. Arterial stiffness, central blood pressures and wave reflections are independent predictors of cardiovascular risk. This study investigates the relation between low-grade...

Turkey reported its first COVID-19 case on March 10, 2020. We present here the mitigation efforts Turkey has undertaken so far, and also review the lessons learned for future proactive strategies. High number of intensive care unit beds and ventilators, national treatment algorithms, governmental support...

Cancer places a considerable burden on society that is reflected in both economic and humanitarian costs. We aimed to estimate the disease burden of cancers in Tunisia using the Disability Adjusted Life Years (DALYs) as a health measure. We performed the methodology suggested in the Global Burden of...

This paper sets out to disprove the German philosopher Hegel’s dictum about people learning nothing from history, by looking at the lessons to be learned for the African Continental Free Trade Area (AfCFTA) from the European Union’s experience of regional integration. Since its foundation in 1957, European...

Background: Whether angiotensin receptor blockers can dose-dependently remodel the arterial wall during long-term treatment has only been rarely studied. Olmesartan (OM) has previously shown a favourable pharmacodynamic profile for such an action. Methods: In this phase 3, multi-centre, double-blind,...

Background: Ultrahigh-frequency ultrasound may represent a powerful tool for investigating the arterial properties of medium and small-size arteries. Aim of this study was: 1) to evaluate intra- and inter-operator reproducibility of radial artery vascular parameters (intima-media thickness –IMT- and...

Objectives: Baroreflex function was found to be impaired in schizophrenia and reduced baroreflex-sensitivity (BRS) was associated with increased mortality. Stiffening of the baroreceptor vessel wall, such as the carotid artery, may lead to reduced activation of the baroreceptors and blunt the baroreflex....

Objective: To assess whether reservoir pressure (Pres) in young individuals with a compliant aorta is uniform throughout the aorta, as has recently been reported in older adults with cardiovascular disease (1). Methods: High fidelity pressure was measured with a Verrata wire (Philips Volcano) in 5 aortic...

Objective: The Mediterranean diet, rich in fruits, legumes and vegetables is a healthy dietary pattern, gaining widely recognition as a non-pharmaceutical mean of cardiovascular disease prevention, due to antioxidant and anti-inflammatory properties. Erectile dysfunction (ED), represents an early marker...

Background: Our aim was to study the predictive power of ICPS risk categories on CV mortality in hemodialysis patients. Methods: In our retrospective cohort study 91 patients were involved from two dialysis centers. Pulse Wave Velocity (PWV), central systolic blood pressure (cSBP) and and central pulse...

Objectives: The objectives of this cross-sectional study was to determine the prevalence of extra/-intracranial stenosis in patients with severe coronary artery disease (CAD) and to analyze how endothelial function and arterial stiffness are related to the presence of intracranial stenosis. Methods:...

This work illustrates the effects of various system parameters on the dynamics of flexible link of revolute-jointed rigid-flexible manipulator. Flexible link is considered as a Euler-Bernoulli beam and finite element based on Langrange approach is employed for dynamic analysis. A comparative study is...

Applying five cultural dimensions, power distance, uncertainty avoidance, in-group collectivism, Bengali value and ethical culture, along with the two fundamental antecedents of Technology Acceptance Model (perceived usefulness and perceived ease of use), this study examined the influence of culture...

A chemical spill into a river presents a significant threat to human health and the aquatic environment. A mathematical model is presented for predicting the chemical concentrations in a river resulting from a chemical spill. A screening risk assessment approach is presented to characterize the risk...

Large-scale adoption of MapReduce applications on public clouds is hindered by the lack of trust on the participating virtual machines deployed on the public cloud. In this paper, we propose IntegrityMR, a multi-public clouds architecture-based solution, which performs the MapReduce-based result integrity...

The final goal of our research is to develop a measurement system for quantitative evaluation of the skillfulness of the lower extremities. In our previous work, we developed the measurement system of the foot movement on the floor with the sitting posture. In this study, we developed a quantitative...

Solutions to basic non-linear limit spectral equation for matrices RT R of increasing dmension are investigated, where R are rectangular random matrices with independent normal entries. The analytical properties of limiting normed trace for the resolvent of RT R are investigated, boundaries of limit...

In a multilingual country like India, a document may contain text words in more than one language. For a multilingual environment, multi lingual Optical Character Recognition (OCR) system is needed to read the multilingual documents. So, it is necessary to identify different language regions of the document...

The Burgers equation and the Camassa-Holm equations can both be recast as the Euler equation for a right-invariant metric on the diffeomorphism group of the circle, the L 2-metric for Burgers and the H 1-metric for Camassa-Holm. Their geometric behaviors are however very different. We present a survey...

The dynamics of solitary waves is studied in intricate domains such as open channels with sharp-bends and branching points. Of particular interest, the wave characteristics at sharp-bends is rationalized by using the Jacobian of the Schwarz–Christoffel transformation. It is observed that it acts in a...

Engraftment syndrome (ES) is a clinical syndrome that occurs in the early neutrophil recovery phase following hematopoietic stem cell transplant (HSCT). Although also described for allogenic HSCT, it is basically diagnosed in the context of autologous HSCT. We retrospectively reviewed 171 consecutive...

Ensuring of the traceability of deliverables is one of effective methods to secure the quality of software. It can verify that the requirements are reflected in the programs. But it has two problems: taking much labor and time, and causing mistakes by human handling. This paper has implemented RETUSS...

Macrovasculature and microvasculature are interrelated, and may influence each other. Microvascular structure is not only the site of vascular resistance but probably also the origin of most of the wave reflections generating increased central systolic blood pressure. Some index of large artery stiffness...

Monitoring of the regional stiffening of the arterial wall may prove important in the diagnosis of various vascular pathologies. The pulse wave velocity (PWV) along the aortic wall has been shown to be dependent on the wall stiffness and has played a fundamental role in a range of diagnostic methods....

Background: We investigate whether peripheral arterial disease (PAD) detected by ankle brachial index (ABI) <0.9 is independently associated with aortic stiffness and lipoprotein (a) [Lp(a)] in elderly subjects free from PAD at baseline. Methods: The present study included 96 lecture attendees (“Continuing...

Background: Mean arterial pressure (MAP) is required for many hemodynamic calculations. Most automated devices do not report MAP and a form factor (FF) is used to estimate it from systolic and diastolic blood pressure (BP). The appropriate choice of FF in the brachial artery is controversial: 0.33 is...

The aim of study was to assess the feasibility of 24-hour PWV analysis in management of patients with renal transplantation (RT). Overall, 41 patients were recruited from the transplant waiting list. All the measurements were performed before and at 1 and 20 weeks after RT. The Pulse Time Index of Norm...

Introduction: It is estimated that currently 17 million deaths annually in the world occur due to cardiovascular disease (CV), about one third of all deaths. 9.4 million are related to arterial hypertension (HA). The use of methods that allow the early identification of structural and functional cardiovascular...