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Background: The cuff sphygmomanometer failed to show consistent alteration in brachial blood pressure with slow-release isosorbide-5-mononitrate(IS-5-MN), even though the drug proved very effective in relieving angina pectoris.Sofar, the effect of orally single dose of slow-release isosorbide-5-mononitrate...

Background: Previously regarded as a measure of pressure wave reflection, central augmentation pressure (AP) may be influenced by the pattern of early ventricular ejection. We examined the relationship of AP to first-phase ejection fraction (EF1), a measure of ventricular ejection up to the time of the...

Objectives: Poor glycemic control during pregnancy is associated with increased adverse perinatal outcomes. Our objective was to characterize the association between glycemic control and arterial stiffness in pregnancy. Methods: In this prospective longitudinal study, women with high-risk singleton...

Background: Perioperative acute kidney injury has been found to occur in 12% of patients undergoing lower limb revascularisation (Arora et al., 2013). The aim of the current double-blinded, randomised and sham-controlled pilot study was to determine the effect of remote ischaemic preconditioning (RIPC)...

Background: Carotid-femoral pulse wave velocity (cfPWV) is predictive of cardiovascular outcomes but clinical interpretation is confounded by blood pressure (BP) interaction. This study proposes a method for PWV pressure dependency measurement suitable for routine clinical or research use. Methods:...

Objectives: Low-dose acetylsalicylic acid (ASA) has been shown to reduce the risk for pre-eclampsia in high-risk pregnancies when prescribed before 16 weeks of gestation. It remains unknown whether this anti-inflammatory agent has effects on arterial stiffness. Our objective was to characterize arterial...

Objective: To examine whether Sympathetic Renal Denervation (RDN) might have an additive value for cardiovascular risk decline beyond lowering blood pressure. Methods: 73 selected patients with resistant hypertension had RDN performed. Arterial stiffness was measured, using applanation tonometry, before...

Introduction: Pressure-Velocity (PU) loops obtained in the descending thoracic aorta (PU-loopsdes) could estimate left ventricular afterload with two remarkable angles: β and GALA (Global Afterload Angle) [1].The aim of this study is to compare PU-loops measured in the ascending aorta (PU-loopsasc) versus...

Objectives: The purpose was to investigate the ability of a new software, developed by our group, to provide continuous measures of arterial diameter from recorded ultrasound video. Methods: Software (MAUI) was developed to assess arterial diameter using active contours to accurately detect the vessel...

Despite the widespread uses in military, smart building, habitat monitoring, Wireless sensor networks (WSNs) just begun showing their superiority in the medical and healthcare domain. Facing same challenges as other applications, deployment of WPANs in medical domain exert many more stringent requirements,...

Rolling bearing is a common mechanical part which is subject to be damaged. It is important to monitor the condition of bearing. An effective mean is to extract faulty features of bearing from the vibration signal. In this paper, a method is introduced to realize intelligent classification of bearing...

Billion-billion dollar spends for the implementation of Information Technology (IT) in rural/village areas of developing countries through the direct-indirect interventions of The United Nations (UN), the World Bank and the International Telecommunication Union (ITU) and so on. Unfortunately, focus has...

DSSN model is a qualitative neuronal model designed for efficient implementation in a digital arithmetic circuit. In our previous studies, we extended this model to support a wide variety of neuronal classes. Parameters of the DSSN model were hand-fitted to reproduce neuronal activity precisely. In this...

We introduce an extension of the factorization-decomposition technique that allows us to manufacture new solvable nonlinear matrix evolution equations. Several examples of such equations are reported.

Background: It’s unknown wheather there is much benefit on central aortic pressure than brachial pressure while long-term administration of hydrochlorothiazide in patients with essential hypertension. Methods: The retrograde analysis was conducted at three of the participating centers in the Felodipine...

Background: Central systolic blood pressure (central-SBP) can be estimated noninvasively and antihypertensive drugs may exert different effects on central-SBP. We investigated the usefulness of carotid systolic blood pressure (carotid-SBP) estimated by form PWV/ABI in blood pressure lowering therapy. Methods:...

Background: The various statin might contribute to a change in arterial stiffness independent of the cholesterol-lowering effects of statin therapy. The aim of this study was to compare the short-term effect between co-administration of simvastatin and ezetimibe (vytorin) and atorvastatin (lipitor) on...

Background: Estimated central blood pressure (BP) predicts cardiovascular mortality independent of brachial BP, but whether central BP may be useful in clinical practice is unknown. This study aimed to test the value of central BP as a management tool for physicians treating patients with essential hypertension. Methods:...

Background: An efficient public health workforce is necessary for improving and maintaining the health of population and such a workforce can be prepared through proper educational programs and trainings. Objectives: The present study aims to investigate the needs in the public health education programs,...

The overhead contact system (OCS) is the power source of electrified railway, it is very important to evaluate the system status accurately to maintain its safe and stable operation. At present, fault tree analysis is the main method of reliability assessment for OCS. Existent methods to establish the...

To become operational, the African Continental Free Trade Area (AfCFTA) must harmonize Rules of Origin (ROO) across Africa’s Preferential Trade Agreements (PTAs) along two dimensions: regime-wide rules and product-specific rules. This paper describes and evaluates these ROO across the major multiple-membership...

Retrospective studies suggest that chimeric antigen receptor T-cell (CAR T) therapy may lead to cardiac injury, but this has not been assessed systematically or prospectively. In this prospective study of 40 patients who received CAR T, we systematically measured high-sensitivity troponin T (hsTropT)...

Aim: Mechanisms through which SGLT-2 inhibitors achieve cardiovascular and renal protection are still unknown. We investigated whether dapagliflozin modulates Na and water balance and systemic and renal vascular parameters like endothelial function, arterial stiffness and renal vasodilating capacity. Methods:...

Purpose/Background/Objective: Arterial stiffness and aortic hemodynamics are independent predictors of adverse cardiovascular events. Indications for Transcatheter Aortic Valve Implantation (TAVI) are increasing in number and Aortic Valve Calcifications (AVC) are an important prognostic factor of TAVI....

Background: Individualized weighing of the risk-benefit of anticoagulation is recommended in patients with atrial fibrillation (AF) that have low established risk scores or, conversely, are at increased risk for bleeding1. Parameters of arterial stiffness and wave reflection could improve risk stratification,...

Background: Pulse waveforms are modified as they propagate along the arterial tree. Small differences in the arterial pathways from the heart to the left and right brachial artery may impact pulse waveform analysis (PWA) for the purpose of hemodynamic assessment. The VaSera VS-1500AU (Fukuda Denshi)...

Background: The literature demonstrates that anger is associated with cardiovascular disease, but the underlying physiological mechanisms remain undefined. Endothelial dysfunction, present in atherosclerosis, has also been associated with anger. Purpose: To examine the association between anger and...

Background: Arterial stiffness, often expressed in terms of pulse wave velocity (PWV), is an important risk factor for cardiovascular disease. PWV can be determined locally and non-invasively, by means of ultrasound. Aim: To assess PWV, local compliance (Cs), distensibility (Ds) and Young’s modulus...

Introduction: Higher aortic stiffness and central blood pressure (BP) are associated with reduced cognitive performance in older adults. Cognitive performance tends to be higher in older women compared with older men, unexplained by differences in years of formal education and/or presence of atherosclerotic...

The need of detecting moving object like human and vehicle by mobile camera is increasing in commerce and industry. Therefore, tradition method of abstracting moving object from still background cannot solve the problem. Though Histogram of Oriented Gradients (HOG) have been widely used for human detection,...

Companies exposed to hazards can be paralleled to building and engineering Structures subjected to physical loads; see. Important analogies can be identified in various specific concepts, e.g., in size effect, instability, fatigue, and in many others.

We investigate the parametric maximum likelihood estimator for truncated data when the truncation value is different according to the observed individual or item. We extend Lehmann’s proof (1983) of the asymptotic properties of the parametric maximum likelihood estimator in the case of independent nonidentically...

Exorbitant computation cost hinders the practical application of recommendation algorithm, especially in time-critical application scenario. Although experiments show that recommendation algorithm based on an integrated diffusion on user-item-tag tripartite graphs can significantly improve accuracy,...

Stock e-exchange prices forecasting is an important financial problem that is receiving increasing attention. This study proposes a novel three-stage nonlinear ensemble model. In the proposed model, three different types of neural-network based models, i.e. Elman network, generalized regression neural...

Mukerjee (1979) introduced structure (k) property of a factorial design. In this article, we introduce structure (k1), structure (k2) and structure (k1k2) properties of a factorial design. We establish properties of each of these structure designs in terms of the incidence and characteristic matrices...

The Einstein field equations for several cosmological models reduce to polynomial systems of ordinary differential equations. In this paper we shall concentrate our attention to the spatially homogeneous diagonal G2 cosmologies. By using Darboux's theory in order to study ordinary differential equations...

Properties of approximate symmetries of equations with a small parameter are discussed. It turns out that approximate symmetries form an approximate Lie algebra. A concept of approximate invariants is introduced and the algorithm of their calculating is proposed.

A new approach to the analysis of wave-breaking solutions to the generalized Camassa-Holm equation is presented in this paper. Introduction of a set of variables allows for solving the singularities. A continuous semigroup of dissipative solutions is also built. The solutions have non-increasing H1 energy...

In this paper, the exponential stability problems are addressed for a class of delayed Cohen-Grossberg neural networks which are also perturbed by some stochastic noises. By employing the Lyapunov method, stochastic analysis and some inequality techniques, sufficient conditions are acquired for checking...

Seismic vulnerability challenges sustainable urbanism. Antioch, Manosque and Oran, three Mediterranean cities destroyed by earthquakes, demonstrate how preservation of urban patrimony protects populations. The methodological pattern “urban seismic patrimonial strategies” cross investment and patrimonial...

Hypertension is associated with endothelial dysfunction and increased cardiovascular risk. Caveolin-1 regulates nitric oxide(NO) signaling by modulating endothelial nitric oxide synthase(eNOS). The purpose of this study was to examine whether HMG-CoA reductase inhibitor improves impaired endothelial...

Background: The measurement of carotid-femoral pulse wave velocity (cfPWV) is useful to predict storke and cardiovascular events in hypetensive patients as our previous cohort study Non-invasive Atheroslerotic evaluation in Hypertension (NOAH) sutdy. As the cfPWV is useful, but not easy to measure, it...

Background: Arterial stiffness has been known as an independent contributory factor for coronary artery disease (CAD). Pulse wave velocity (PWV) is widely accepted as a simple non-invasive measure of arterial stiffness. The aim of our study was to test whether abnormal PWV could identify patients with...