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To define the vascular role of the mineralocorticoid receptor (MR) in cardiovascular pathophysiology, we generated a conditional transgenic mouse model with MR overexpression in the endothelium. We previously described increase sensitivity to several vasoconstrictors in mesenteric arteries such as in...

An age-related increase in systolic blood pressure and similarities in the consequences of hypertension and aging on arterial structure/mechanics have been reported, particularly in larger arteries. As the structural/mechanical properties of smaller resistance vessels in the context of advancing physiological...

Background. Experimental cerebral ischemia and organ culture of cerebral arteries result in enhanced expression of endothelin ETB receptors in smooth muscle cells. The present study was designed to evaluate the involvement of calcium-calmodulin dependent protein kinase (CAMK) on the expression of endothelin...

For analyzing longitudinal ordinal response data, many methods are available to take into account the correlations between responses of the same individual where different methods use different approaches. One of the methods to consider this correlation is the transition (Markov) model. In this paper,...

Improvement of the work efficiency is demanded by aging and reducing of the working population in the construction field, so that some automation technologies are applied to construction equipment, such as bulldozers and excavators. However, not only the automation technologies but also expert skills...

We study exponentiability of the infinite polynomials with maximal degree 2 of cration and annihilation operators, which give a Fock Space-representation of the coplexification of the affine symplectic group.

This prospective study assessed the prevalence and genetic analysis of α- and β-thalassemia and sickle cell anemia (SCA) in Southwest Iran. Hematological indices were measured in 17,581 couples living in Khuzestan Province, Southwest Iran. Individuals with mean corpuscular volume <80, mean corpuscular...

The introduction of novel agents, characterized by favorable toxicity profiles and higher manageability compared to conventional drugs employed in the past, has considerably changed the treatment paradigm for multiple myeloma. Continuous therapy currently represents the standard approach for myeloma...

Background: Essential hypertension is characterised by alterations in haemodynamics. Hence haemodynamic profiling could lead to improved blood pressure (BP) control in these patients. We tested if baseline haemodynamic indices predict the BP lowering effects of different classes of antihypertensive drugs...

Leakage of the important data in mobile terminals by mal-applications is becoming a serious threat. The users must be careful not to install mal-applications. Application markets provide the application’s reviews and using permissions at the application downloading. However, the most of users check the...

In this paper we study Lie symmetries, Kac-Moody-Virasoro algebras, similarity reductions and particular solutions of two different recently introduced (2+1)-dimensional nonlinear evolution equations, namely (i) (2+1)-dimensional breaking soliton equation and (ii) (2+1)-dimensional nonlinear Schrödinger...

Solutions of the Schrödinger equation for a particle with a tensor-like mass are considered. It is shown that the problem of determination of the coherent states in this case is reduced to integration of the nonlinear system of ordinary differential equations.

While it has been correctly noted that the expression “soft computing” is employed in a variety of senses and characterizations to designate a wide array of technologies, we argue that the original motivation for the introduction of soft-computing methods was the need to cope with the complexity of existing...

Dihydromyricetin (DHM) dramatically improved the quality of life for Streptozotocin (STZ)-induced diabetic rats and significantly increased the activity of antioxidant enzymes in the liver. Moreover, DHM successfully ameliorated diabetes-induced liver damage by suppression of apoptosis in the liver,...

This study was aimed to determine the risk factors associated with COVID-19 infection among contacts of index cases in Saudi Arabia. This unmatched case–control study was conducted among contacts of confirmed COVID-19 cases in April and May 2020 in Al-Madinah, Saudi Arabia. A total of 118 cases and 115...

The notion of solvable structure is generalized in order to exploit the presence of an 𝔰𝔩(2, ℝ) algebra of symmetries for a kth-order ordinary differential equation ℰ with k > 3. In this setting, the knowledge of a generalized solvable structure for ℰ allows us to reduce ℰ to a family of second-order...

We study nonlocal symmetries of Plebański’s second heavenly equation in an infinite-dimensional covering associated to a Lax pair with a non-removable spectral parameter. We show that all local symmetries of the equation admit lifts to full-fledged nonlocal symmetries in the infinite-dimensional covering....

We associate Hamiltonian homological evolutionary vector fields – which are the non-Abelian variational Lie algebroids’ differentials – with Lie algebra-valued zero-curvature representations for partial differential equations.

Introduction: To the best of our knowledge, any studies evaluated potential influence on peripheral arterial stiffness, measured by pulse wave velocity (PWV), of percoutaneous coronary intervention (PCI) and stenting. Methods: 150 patients were enrolled and underwent coronary angiography. In 68 patients...

Background: Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide production and is associated with endothelial dysfunction. Elevated plasma levels of ADMA have been demonstrated in patients with hypertension. The aim of the present study was to investigate the relationship between ADMA...

Introduction: Patients with nocturnal blood pressure (BP) that fails to decline ≥10% compared with daytime BP (non-dippers) have increased mortality risk. This may be related to increased arterial stiffness and raised central BP whilst supine. This study aimed to test this hypothesis. We also sought...

It has been reported that augmentation index (AIx) increases with age, but that the increase is more prominent in younger subjects [1], and may even decrease with age in individuals over 50yrs [2]. We undertook a meta-analysis of the published literature of 9,551 individuals (5,659 male), aged 4 to 91...

The concept of system signature is widely used for comparing of mixed (coherent) systems. In practical situa- tions, it is usually impossible to compare mixed systems. To do this, some partial orders are considered in the literature. In this paper, we define a new concept of stochastic order for comparing...

As the cost for wireless sensors and wireless sensor networks (WSNs) have decreased, they have become more ubiquitous; they are increasingly being used in many applications such as security, structural monitoring and environmental monitoring. Many WSN applications employ a random sensor deployment to...

In theoretical computer science, the Turing machine was introduced as a simple mathematical model of computers in 1936, and has played a number of important roles in understanding and exploiting basic concepts and mechanisms in computing and information processing. After that, the development of the...

This paper chooses 198 listed companies in strategic emerging industries, using DEA model to study the efficiency of equity financing, and carries on efficiency analysis, investment redundancy and output shortage analysis and industry comparative analysis. The results show that the efficiency of equity...

We consider a constrained system of four rigid bodies located in axisymmetric potential and gyroscopic force fields and interacting by means of angular velocities. We describe an integrable case (not in Liouville sence!) when 12-dimensional phase space of the above system is fibered by the coisotropic...

We study conditions for a sequence of Appell polynomials to be a basis on a sequence space.