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Research Article

Perception toward Biosimilars and Nonmedical Switching: A Cross-sectional Survey among Arab Rheumatologists

Mohammed A. Omair, Humaid Al Wahshi, Jamal Al Saleh, Farida Al Balushi, Mostafa Zayed, Maha A. Omair, Eduardo Mysler
Pages: 179 - 185
Objective: The aim of this study is to assess the level of knowledge and acceptance for biosimilars and nonmedical switching in Arab rheumatologists. Methods: A cross-sectional survey was conducted during the Arab League Against Rheumatism conference using a structured questionnaire consisting of 17...

Body and Brain Training for Falls Prevention

Henrik Hautop Lund, Yan-Xin Liu, Massimiliano Leggieri
Pages: 179 - 183
The paper presents the pilot test of the Moto Tiles Body & Brain Test combined with automatically generated individualized training protocols. The test is performed with seniors (avg. 80 years old) with mild dementia in senior care centers in Roskilde, Denmark. The seniors performed pre- and post-test...
Research Article

Virtual Screening and Inhibition of Middle East Respiratory Syndrome Coronavirus Replication by Targeting Papain-like Protease

Mahmoud Kandeel, Byoung Kwon Park, Mohamed A. Morsy, Katharigatta N. Venugopala, Kentaro Oh-hashi, Mohammed Al-Nazawi, Hyung-Joo Kwon
Pages: 179 - 187
Infection by the emerging, potentially zoonotic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) presents a severe health hazard to humans and is often fatal. Given the lack of particular medicines against MERS-CoV, drug discovery studies are needed to bridge this knowledge gap. In this study,...

A New Set of Admitted Transformations for Autonomous Stochastic Ordinary Differential Equations

Sergey V. Meleshko, Eckart Schulz
Pages: 179 - 196
This paper investigates symmetries of autonomous ordinary stochastic differential equations. Change of time includes the stochastic process itself, and is uniquely determined by the transformation of the spatial variable. As a particular feature, the time change by an admitted Lie symmetry group may...

A Note on the Gauss Decomposition of the Elliptic Cauchy Matrix

L. Fehér, C. Klimčík, S. Ruijsenaars
Pages: 179 - 182
Explicit formulas for the Gauss decomposition of elliptic Cauchy type matrices are derived in a very simple way. The elliptic Cauchy identity is an immediate corollary.

Solutions of the (2 + 1)-Dimensional KP, SK and KK Equations Generated by Gauge Transformations from Nonzero Seeds

Jingsong He, Xiaodong Li
Pages: 179 - 194
By using gauge transformations, we manage to obtain new solutions of (2 + 1)-dimensional Kadomtsev–Petviashvili (KP), Kaup–Kuperschmidt (KK) and Sawada–Kotera (SK) equations from nonzero seeds. For each of the preceding equations, a Galilean type transformation between these solutions u2 and the previously...

The Mixed Kuper-Camassa-Holm-Hunter-Saxton Equations

Ling Zhang, Beibei Hu
Pages: 179 - 187
In this paper, a mixed Kuper-CH-HS equation by a Kupershmidt deformation is introduced and its integrable properties are studied. Moreover, that the equation can be viewed as a constraint Hamiltonian flow on the coadjoint orbit of Neveu-Schwarz superalgebra is shown.

New Integrable and Linearizable Nonlinear Difference Equations

R. Sahadevan, G. Nagavigneshwari
Pages: 179 - 190
A systematic investigation to derive nonlinear lattice equations governed by partial difference equations (PΔΔE) admitting specific Lax representation is presented. Further it is shown that for a specific value of the parameter the derived nonlinear PΔΔE's can be transformed into a linear PΔΔE's...
Conference Abstract

P3.03 IMPACT OF SMOKING ON ERECTILE FUNCTION AND ARTERIAL STIFFNESS IN MIDDLE-AGED SMOKERS WITHOUT OTHER MAJOR CARDIOVASCULAR RISK FACTORS

N. Ioakeimidis, C. Vlachopoulos, D. Terentes-Printzios, A. Aggelis, K. Baou, G. Antoniou, K. Rokkas, C. Stefanadis
Pages: 180 - 181
Purpose: Erectile dysfunction (ED) may be an early manifestation of generalized vascular disease. Cigarette smoking is an important modifiable cardiovascular risk factor and pathophysiological mechanisms may include a stiff vascular tree. The association of smoking with ED and functional changes in smokers...
Conference Abstract

P3.02 GLUCOSE METABOLISM IMPAIRMENT IN METABOLIC SYNDROME IS LINKED WITH INCREASED PULSE WAVE VELOCITY

A.L. Lieber, C. Vesin, M.E. Safar, B.I. Levy, J. Blacher
Pages: 180 - 180
Introduction: Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors. The specificity of each component of metabolic syndrome improves its management. Objective: Do patients with MetS have arterial modifications? Which MetS components are they most closely linked to? Materials and methods:...
Conference Abstract

P11.09 SYSTEMIC ARTERIAL PROPERTIES IN WOMEN 3 YEARS AFTER A PRE-ECLAMPTIC PREGNANCY

M.E. Estensen, E.W. Remme, A. Swillens, T. Henriksen, O.A. Smiseth, L. Gullestad, P. Segers, S. Aakhus
Pages: 180 - 181
Conference Abstract

P3.01 CAROTID ARTERY INTIMA-MEDIA COMPLEX INCREASE IN PATIENTS WITH METABOLIC SYNDROME AND DIFFERENT BRACHIAL ARTERY REACTIVITY DURING REACTIVE HYPERAEMIA TEST: 2 YEARS FOLLOW-UP RESULTS

V.V. Vikentyev, O.A. Polikina
Pages: 180 - 180
Patients having different risk factors for coronary heart disease (CHD), as well as those with metabolic syndrome, are known to have increased carotid artery (CA) intima-media complex thickness (IMT) index, comparing to healthy subjects. Recently, the significant correlation between IMT, changes in flow-mediated...
Conference Abstract

P7.06 GENDER DIFFERENCE IN CARDIOVASCULAR RISK: ROLE OF BLOOD PRESSURE AMPLIFICATION

V. Regnault, P. Lacolley, M.E. Safar, F. Thomas, B. Pannier, N. Danchin
Pages: 180 - 180
Conference Abstract

P3.13 ROLE OF THE SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) IN CELL DIFFERENTIATION: CONSEQUENCES IN ATHEROSCLEROSIS

A. Filip, S. Taleb, F. Fève, J. Magdalou, S. Jalkanen, Z. Mallat, P. Lacolley, N. Mercier
Pages: 180 - 180
Conference Abstract

P2.12 THE ROLE OF INSULIN ON FUNCTION OF RESISTANCE ARTERIES FROM OBESE YOUNG WOMEN AT RISK OF ‘DIABETES’ AND CONTROLS

M. Banerjee, C. Austin, V. Charlton-Menys, W.F. Fraser, P. Pemberton, R.A. Malik, J.K. Cruickshank
Pages: 180 - 180
Objectives: Vascular dysfunction is common in type 2 diabetes and obesity. The functional role of hyperinsulinaemia on human blood vessels in obese individuals remains unclear. We hypothesised that in young women, change in vessel function in a hyperinsulinaemic milieu would be influenced more by adiposity...
Conference Abstract

P11.07 DIFFERENCE BETWEEN SYSTOLIC AND DIASTOLIC CAROTID ARTERY STIFFNESS IS INDEPENDENTLY ASSOCIATED WITH LEFT VENTRICULAR MASS INDEX IN HEALTHY MIDDLE-AGED SUBJECTS

K.D. Reesink, E. Hermeling, S.J. Vermeersch, E.R. Rietzschel, M.L. De Buyzere, T. Gillebert, R.J. van de Laar, I. Ferreira, A.P.G. Hoeks, L.M. van Bortel, R.S. Reneman, P. Segers
Pages: 180 - 180

Non-isospectral lattice hierarchies in 2 + 1 dimensions and generalized discrete Painlevé hierarchies

P.R. Gordoa, A. Pickering, Z.N. Zhu
Pages: 180 - 196
In a recent paper we introduced a new 2 + 1-dimensional non-isospectral extension of the Volterra lattice hierarchy, along with its corresponding hierarchy of underlying linear problems. Here we consider reductions of this lattice hierarchy to hierarchies of discrete equations, which we obtain once again...

Soliton Collisions and Ghost Particle Radiation

Hiêú D. Nguyêñ
Pages: 180 - 198
This paper investigates the nature of particle collisions for three-soliton solutions of the Korteweg-de Vries (KdV) equation by describing mathematically the interaction of soliton particles and generation of ghost particle radiation. In particular, it is proven that a collision between any two soliton...

Nonlinear Quantum Dynamical Equation for Self-Acting Electron

V.P. Oleinik
Pages: 180 - 189
From the action principle, the quantum dynamical equation is obtained both relativistically and gauge invariant, which is analogous to the Dirac equation and describes behaviour of an arbitrary number of self-acting charged particles. It is noted that solutions of this equation are indicative of the...
Research Article

Carotid haemodynamics during sympathetic nervous system stimulation via handgrip and cold pressor testing in young healthy subjects: A feasibility study

F.J. Londono, T.S. Klopmeijer, D. Georgakopoulos, E.G. Lovett, L. Van Bortel, P. Segers
Pages: 178 - 188
Introduction: Assessing arterial and haemodynamic properties in response to a physiological perturbation might provide additional information on an individual’s “vascular health”. The aim of this study was to assess the feasibility of measuring changes in carotid stiffness and haemodynamics in response...

DAMA: A Dynamic Classification of Multimodal Ambiguities

Patrizia Grifoni, Maria Chiara Caschera, Fernando Ferri
Pages: 178 - 192
Ambiguities represent uncertainty but also a fundamental item of discussion for who is interested in the interpretation of languages and it is actually functional for communicative purposes both in human–human communication and in human–machine interaction. This paper faces the need to address ambiguity...

Efficacy of DAAs in the Treatment of Chronic HCV: Real-World Data from the Private Health-Care Sector of the Kingdom of Saudi Arabia

Almoutaz Hashim, Fadia Almahdi, Emad Aldin Albaba, Ohoud Barkia, Reem Alkasam, Asmaa Almahmoud, Ahmed Nabil, Ayman Alsulaimani, Mahmoud Mosli
Pages: 178 - 183
Background and Aim: The hepatitis C virus (HCV) is considered a global health challenge that requires urgent interventions for prevention and control. In this study, we aimed to evaluate the effectiveness of direct-acting antiviral agents (DAAs) for HCV-infected patients in the Kingdom of Saudi Arabia...

Impact of Population Emigration from Wuhan and Medical Support on COVID-19 Infection in China

Yang Yao, Yao Tian, Jing Zhou, Xin Diao, Ligai Di, Shengyu Wang
Pages: 178 - 185
Background: The novel Coronavirus Disease 2019 (COVID-19) infection broken out in Wuhan. We aimed to analyse the impact of medical support and population emigration from Wuhan on the cure rate and mortality of COVID-19 infection in China and to provide early warning on the developmental trend of the...
Conference Abstract

P2.11 ASSESSING VENTRICULAR-VASCULAR INTERACTIONS IN GIRLS WITH TURNER SYNDROME: A PILOT STUDY

T.J. Bradley, C.S. O’Gorman, C. Slorach, M.K. Friedberg, L. Mertens, G.D. Wells, J. Hamilton
Pages: 179 - 179
Objectives: Women with Turner Syndrome (TS) have increased incidence of cardiovascular disease, thought to be related to a clustering of risk factors including insulin resistance, hypertension, obesity and dyslipidemia. The aim of this study was to non-invasively determine and compare ventricular and...
Conference Abstract

P11.06 FIBRONECTIN, BUT NOT LAMININ CONTENT IS INCREASED IN THE TUNICA MEDIA OF SUBCUTANEOUS SMALL RESISTANCE ARTERIES OF PATIENTS WITH ESSENTIAL HYPERTENSION

C. De Ciuceis, L.F. Rodella, D. Rizzoni, E. Porteri, R. Rezzani, G.E.M. Boari, E. Borsani, G. Favero, C. Platto, G.A.M. Tiberio, S.M. Giulini, E. Agabiti Rosei
Pages: 179 - 180
Conference Abstract

P2.10 METABOLIC SYNDROME DOES NOT HAVE AN INDEPENDENT IMPACT ON ULTRASOUND INDICES OF PRECLINICAL CARDIOVASCULAR DISEASE

E. Malshi, C. Morizzo, M. Kozakova, C. Palombo
Pages: 179 - 179
Background: whether metabolic syndrome (MetS) has an independent impact on development of cardiovascular (CV) disease is uncertain. Aim: to evaluate indices of preclinical CV disease in subjects with MetS. Methods: we studied 160 subjects: 50 with MetS (ATP III criteria, age 49±12, BMI 36±7, 12 diabetics)...
Conference Abstract

P7.04 AORTIC STIFFNESS IS ASSOCIATED WITH ALBUMINURIA IN THE GENERAL POPULATION

V. Selvarajah, L.A. Tomlinson, J. Smith, Y. Yasmin, J.R. Cockcroft, I.B. Wilkinson, C.M. McEniery
Pages: 179 - 179
Conference Abstract

P11.05 ASSESSING VENTRICULAR-VASCULAR INTERACTIONS AFTER STENTED COARCTATION

G.J. Morgan, C. Slorach, W. Hui, T. Sarkola, K.J. Lee, R. Chaturvedi, L.N. Benson, L. Mertens, T.J. Bradley
Pages: 179 - 179
Conference Abstract

P2.09 INCREASED CAROTID INTIMA MEDIA THICKNESS AND WAVE REFLECTION IN PATIENTS WITH INTRACRANIAL ANEURYSMS

F. Santini, C. Morizzo, C. Martini, E. Malshi, M. Caniglia, M. Kozakova, G. Parenti, C. Palombo
Pages: 179 - 179
Background: whether or not the presence of intracranial aneurysms (IAs) is associated with alterations in systemic arteries is not known. Aim of the study was to evaluate morphology and distensibility of common carotid artery (CCA) in patients with IAs and in a control group of comparable age, gender...
Conference Abstract

P11.04 VASCULAR STIFFNESS IS INCREASED IN ANTIPHOSPHOLIPID SYNDROME: SIGNIFICANCE AND CLINICAL ASSOCIATIONS

D. Wahl, P. Salvi, A. Kearney-Schwartz, V. Bravetti, T. Moline, E. Farese, V. Regnault, P. Lacolley, M. Valla, S. Zuily, C. Perret-Guillaume, T. Lecompte, A. Benetos
Pages: 179 - 179
Conference Abstract

P2.08 INTERRELATIONSHIPS BETWEEN METABOLIC SYNDROME, ERECTILE DYSFUNCTION AND EARLY ATHEROSCLEROSIS

N. Ioakeimidis, C. Vlachopoulos, G. Antoniou, K. Baou, D. Terentes-Printzios, A. Aggelis, I. Dima, P. Xaplanteris, G. Lazaros, C. Stefanadis
Pages: 179 - 179
Purpose: Men with metabolic syndrome (MetS) have an increased prevalence of erectile dysfunction (ED). Large artery stiffness is a marker of vascular wall changes associated with MetS. Aim of the study was to investigate associations between MetS, ED and changes in large artery properties. Methods:...
Conference Abstract

P11.03 PULSE PRESSURE PARTIALLY EXPLAINS THE INCREASED INCIDENT CARDIOVASCULAR DISEASE ASSOCIATED WITH INFLAMMATION IN TYPE 1 DIABETES: A 12-YR FOLLOW-UP STUDY

J.W.M. Nin, A. Jorsal, I. Ferreira, C.G. Schalkwijk, M.H. Prins, H.-H. Parving, L. Tarnow, P. Rossing, C.D.A. Stehouwer
Pages: 179 - 179
Conference Abstract

P3.07 QUANTITATIVE METHOD TO DETERMINE SMOOTH MUSCLE CELL ORIENTATION IN VITAL ARTERIES

B. Spronck, J.J. Merken, W. Kroon, R.T.A. Megens, K.D. Reesink, T. Delhaas
Pages: 179 - 179

Neutral Networks-Based Adaptive Fixed-Time Consensus Tracking Control for Uncertain Multiple AUVs

Lin Zhao, Yingmin Jia, Jinpeng Yu
Pages: 179 - 182
This paper is concerned with the fixed-time consensus tracking problem for multi-AUV (autonomous underwater vehicle) systems with uncertain parameters and external disturbances. Firstly, a fixed-time terminal sliding mode is proposed, which can avoid the singularity problem. Then, a continuous distributed...

A Comparative Study of Inter-firm Transactional Relationship between Kyohokai and Yokokai

Takao Ito, Makoto Sakamoto, Satoshi Ikeda, Rajiv Mehta, Yasuo Uchida
Pages: 179 - 183
Although two major Japanese manufacturers, Toyota and Mazda, compete in the automotive market, their corporate performance, respectively, is different because the internal resources and the way they coordinate interrelationships among their network partners is known to be divergent. Both these two companies...

Wenzhou Real Estate Bubble and Rupture Risk Warning

Anping Pan, Chongfu Huang, Dehua Jiang
Pages: 179 - 188
It is known to us all that the excessive bubble in the real estate market can seriously affect the normal development of the national economy, which could cause the hidden dangers of financial crisis. In 2011, A wave of defaults destabilized markets across Wenzhou, which punctured the property price...
Short Communication

A Remark on Rational Isochronous Potentials

Oleg A. Chalykh, Alexander P. Veselov
Pages: 179 - 183
We consider the rational potentials of the one-dimensional mechanical systems, which have a family of periodic solutions with the same period (isochronous potentials). We prove that up to a shift and adding a constant all such potentials have the form U(x) = 1 2 2 x2 or U(x) = 1 8 2 x2 + c2 x-2 .