Proceedings of the 2024 Brawijaya International Conference (BIC 2024)

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Urea And Creatinine Transport by Polymer Inclusion Membrane

Authors
Ulfa Andayani1, *, Barlah Rumhayati1, Thalia Salsabilla1, Bresnia Prameswari1
1Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Brawijaya, Malang, 65145, Indonesia
*Corresponding author. Email: ulfasuryadi@ub.ac.id
Corresponding Author
Ulfa Andayani
Available Online 11 November 2025.
DOI
10.2991/978-94-6463-854-7_17How to use a DOI?
Keywords
PIM; % transport; Urea; Creatinine; Hemodialysis
Abstract

This study aims to determine the optimal composition for PIM (Polymer Inclusion Membrane) used for the transport of urea and creatinine. The composition of PIM consists of CTA (Cellulose triacetate) as the basic polymer, TBP (Tributhyl phosphate) as a carrier compound, and 1-Decanol as a plasticizer. The best composition was determined based on the % transport value of urea and creatinine. The studied PIM composition ratio of CTA: TBP:1-Decanol were (7:2:1), (8:1:1), (6:3:1), and (5:4:1). Furthermore, PIM was applied to transport urea and creatinine with the receiving phase of PBS (phosphate buffer saline) solution pH 7.4. Urea and creatinine concentrations in the feed phase studied were 50, 500, and 1000 mg/L. The transport process was carried out for 4 hours. The amount of urea and creatinine transported was analyzed by UV-visible spectrophotometry at the maximum wavelength of each. Urea was analyzed using a 4-dimethylamino benzaldehyde reagent, while creatinine was analyzed using a picric acid reagent. The best membrane competition is CTA: TPB: 1-Decanol 5:4:1; this is because membranes can block the urea and creatinine permeases. The transport results showed that PIM with a composition ratio of (CTA: TBP: 1-Decanol) 8:1:2 exhibited the best performance in transporting urea and creatinine. The highest transport percentage of 48.1% was achieved in the 1000 mg/L urea feed phase, and 46.7% was completed in the 75 mg/L creatinine feed phase.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2024 Brawijaya International Conference (BIC 2024)
Series
Atlantis Advances in Applied Sciences
Publication Date
11 November 2025
ISBN
978-94-6463-854-7
ISSN
3091-4442
DOI
10.2991/978-94-6463-854-7_17How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Ulfa Andayani
AU  - Barlah Rumhayati
AU  - Thalia Salsabilla
AU  - Bresnia Prameswari
PY  - 2025
DA  - 2025/11/11
TI  - Urea And Creatinine Transport by Polymer Inclusion Membrane
BT  - Proceedings of the 2024 Brawijaya International Conference (BIC 2024)
PB  - Atlantis Press
SP  - 220
EP  - 231
SN  - 3091-4442
UR  - https://doi.org/10.2991/978-94-6463-854-7_17
DO  - 10.2991/978-94-6463-854-7_17
ID  - Andayani2025
ER  -