Proceedings of the International Biological Conference in Mongolia 2025 (IBCM 2025)

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Biological Activities of Purified Xylooligosaccharides Derived from Food Industry by-products

Authors
Odgerel Chinbat1, *, Purevdulam Erdenetsog1, Battogtokh Chimeddorj2, Munkhjargal Burenjargal3, Munkhtsetseg Janlav1
1Department of Biochemistry, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
2Department of Microbiology, Infection Prevention and Control, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
3Department of Chemistry, School of Arts and Sciences, National University of Mongolia, Ulaanbaatar, Mongolia
*Corresponding author. Email: fbm17f014@gt.mnums.edu.mn
Corresponding Author
Odgerel Chinbat
Available Online 17 September 2025.
DOI
10.2991/978-94-6463-837-0_9How to use a DOI?
Keywords
Xylooligosaccharides (XOS); enzymatic hydrolysis; food by-products; prebiotic activity; gut microbiota; antioxidant capacity; circular bioeconomy
Abstract

This study aimed to evaluate the biological activities of purified xylooligosaccharides (XOS) derived from food industry by-products using a combination of biochemical, chromatographic, and in vivo experimental approaches. XOS were extracted from wheat bran and brewery’s spent grains via enzymatic hydrolysis following microwave-assisted pretreatment. The purity, degree of polymerization, and composition of XOS were confirmed by TLC, HPLC and FTIR. In vivo experiments were conducted on rats receiving 400 mg/kg of purified XOS for 18 days. Key results demonstrated that XOS administration significantly reduced serum cholesterol, triglycerides, and LDL levels, and enhanced SCFA production and gut microbiota diversity, particularly Bifidobacterium spp and Lactobacillus spp. The antioxidant activity was confirmed through DPPH scavenging assay. These findings support the potential application of XOS as a functional food ingredient with prebiotic and metabolic benefits. Valorizing agro-industrial by-products into bioactive compounds like XOS contributes to sustainable health interventions and circular bioeconomy development.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Biological Conference in Mongolia 2025 (IBCM 2025)
Series
Advances in Biological Sciences Research
Publication Date
17 September 2025
ISBN
978-94-6463-837-0
ISSN
2468-5747
DOI
10.2991/978-94-6463-837-0_9How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Odgerel Chinbat
AU  - Purevdulam Erdenetsog
AU  - Battogtokh Chimeddorj
AU  - Munkhjargal Burenjargal
AU  - Munkhtsetseg Janlav
PY  - 2025
DA  - 2025/09/17
TI  - Biological Activities of Purified Xylooligosaccharides Derived from Food Industry by-products
BT  - Proceedings of the International Biological Conference in Mongolia 2025 (IBCM 2025)
PB  - Atlantis Press
SP  - 121
EP  - 135
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-837-0_9
DO  - 10.2991/978-94-6463-837-0_9
ID  - Chinbat2025
ER  -