A Research on the Interactions Between Common Foods and Oral Drugs and Clinical Prevention and Management Strategies

DOI

10.2991/978-2-38476-551-5_64How to use a DOI?

Keywords

Food-drug interactions; pharmacokinetics; pharmacodynamics; clinical pharmacy; patient education; dietary management

Abstract

In modern medicine, it’s really important to know whether oral drugs are effective and safe. This is highly affected by diet, which is a constant and very complicated factor. Food - drug interactions (FDIs) are often ignored, but they can cause problems, from treatment not working to life - threatening situations. This paper explores how common foods interact with oral medicines, helping clinicians and patients understand such interactions by focusing on key Pharmacokinetics (PK) and Pharmacodynamics (PD) mechanisms. PK changes stem from dietary impacts on gastric acidity, gastric emptying, or direct drug-food mixing, plus altered metabolism via intestinal/hepatic CYP enzyme induction/inhibition. PD mechanisms involve drug antagonism or synergy at action sites. Examples include grapefruit juice (inhibits CYP3A4, raising statin levels), dairy (chelates tetracyclines, reducing absorption), vitamin K (antagonizes warfarin), and tyramine-rich foods (cause hypertensive crisis with MAOIs). The paper summarizes these interactions in 4 tables and recommends robust clinical management strategies: proactive screening, nursing-led risk assessment, patient education (e.g., teach-back), clear labels, and patient empowerment via dietary tools/self-monitoring. Conclusion:Integrating FDI management into daily care is essential for optimal outcomes, minimizing harm amid prevalent polypharmacy and diverse diets.

Copyright

© 2026 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Shijun Yuan
PY  - 2026
DA  - 2026/03/26
TI  - A Research on the Interactions Between Common Foods and Oral Drugs and Clinical Prevention and Management Strategies
BT  - Proceeding of 2025 8th International Conference on Humanities Education and Social Sciences (ICHESS 2025)
PB  - Atlantis Press
SP  - 601
EP  - 609
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-551-5_64
DO  - 10.2991/978-2-38476-551-5_64
ID  - Yuan2026
ER  -