Effect of Dahlia Tuber Inulin Creamer on Urea and Creatinine Levels In Rat: A Study on Kidney Function and Hyperlipidemia Prevention

DOI

10.2991/978-94-6463-664-2_24How to use a DOI?

Keywords

creamer; creatinine; dahlia tuber; inulin; urea

Abstract

The administration of a high-fat creamer will cause hyper-lipidemia, an atherosclerosis risk factor. If atherosclerosis occurs in the renal arteries, it can cause impaired kidney function. Inulin, a prebiotic, can be used as a creamer ingredient to produce a low-fat creamer. This study aims to determine the effectiveness of dahlia tuber inulin creamer on urea and creatinine. This study involved 20 male rats (aged 2-3 months, 150–200 grams), divided into four groups: Group I received standard food only; Group II received inulin creamer; Group III received creamer without inulin; and Group IV received commercial creamer. Serum urea and creatinine levels were measured using the colorimetric method. The results of the analysis using ANOVA (p < 0.05) showed that there was a significant difference in creatinine levels, followed by the LSD test, and a significant difference was obtained between groups III and IV with group I. Meanwhile, the results of the Kruskal-Wallis analysis did not show significant differences in urea levels between the groups. This study concluded that inulin was effective in preventing an increase in creatinine levels in rats given creamer.

Copyright

© 2025 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Ismawati Ismawati
AU  - Saryono Saryono
AU  - Mukhyarjon Mukhyarjon
AU  - Nabella Suraya
AU  - Lunari Kesya
AU  - Dinda Salsabila
AU  - Cantika Natswa Deanra
PY  - 2025
DA  - 2025/03/31
TI  - Effect of Dahlia Tuber Inulin Creamer on Urea and Creatinine Levels In Rat: A Study on Kidney Function and Hyperlipidemia Prevention
BT  - Proceedings of the 1st International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2024)
PB  - Atlantis Press
SP  - 256
EP  - 264
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-664-2_24
DO  - 10.2991/978-94-6463-664-2_24
ID  - Ismawati2025
ER  -