Development of Eco-Friendly Nanoparticles for Sustainable Drug Delivery: A Comprehensive Review

DOI

10.2991/978-94-6463-813-4_11How to use a DOI?

Keywords

Eco-Friendly Nanoparticles; Computer Simulation; Nanoinformatics; Poly- d; l-lactide-co-glycolide (PLGA); Healthcare Innovations; Poly-e-caprolactone (PCL); Polylactic Acid (PLA)

Abstract

The need for biodegradable nanoparticles as part of environmentally friendly drug delivery has grown tremendously over the years. These nanoparticles have several advantages biocompatibility, low toxicity, and rather minimal negative effects on the environment due to their lipid, protein, and polysaccharide origin. Some common examples of such systems are referred to in the following section to exemplify the versatility of their application. Computer-aided mechanisms including molecular modeling, simulation of nanodevice, and high-end computing are essential to nanoparticle design. These approaches afford accurate prediction of the nanoparticle’s actions, high load with the drug, precise release, and improved interactions of nanoworld with biological systems. In this regard, there is still a long way to go in reaching large-scale industrial applications of biodegradable nanoparticles due to problems related to the reproducibility, efficiency, and cost of these nanocarriers, as well as the compliance of industrial products with the relevant national and international standards. Green synthesis techniques and computational methods used in the synthesis process offer themselves as possible solutions to these challenges as progress in the quest for economic and environmentally friendly solutions is made. From this review, it can be seen that there are tremendous opportunities for biodegradable material and computation in an enhanced green drug delivery system. Solving current issues will thus create a way for the integration of green nanoparticles into the life of healthcare facilities and the general environment for health improvement.

Copyright

© 2025 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Uttam Prasad Panigrahy
AU  - Krishna Kumar Bharti
AU  - Sunit Kumar Gupta
AU  - Bhaskarjyoti Saha
PY  - 2025
DA  - 2025/08/13
TI  - Development of Eco-Friendly Nanoparticles for Sustainable Drug Delivery: A Comprehensive Review
BT  - Proceedings of the International symposium on Sustainable Drug Design and Nanoparticle development: Quantum and Computational Perspectives (SDDNDQCP 2025)
PB  - Atlantis Press
SP  - 139
EP  - 164
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-813-4_11
DO  - 10.2991/978-94-6463-813-4_11
ID  - Panigrahy2025
ER  -