Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)

6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)

📍Yogyakarta, Indonesia🗓️ 30-31 July 2025
<Previous Article In Volume
Next Article In Volume>

Treatment Adherence and Factors Influencing the Success of Tuberculosis Therapy: A Systematic Review

Authors
Fransiskus Andriyani Djemahu1, Chairun Wiedyaningsih2, *, Anna Wahyuni Widayanti2
1Master Programme in Pharmacy Management Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
2Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
*Corresponding author. Email: chairun_wied@ugm.ac.id
Corresponding Author
Chairun Wiedyaningsih
Available Online 4 September 2026.
DOI
10.2991/978-94-6239-762-0_24How to use a DOI?
Keywords
Tuberculosis; Treatment adherence; Family support; Healthcare worker; Determinants
Abstract

Tuberculosis (TB) remains a major public health challenge worldwide, with treatment adherence playing a critical role in determining therapeutic success. However, non-adherence to TB medication remains a persistent obstacle, particularly in countries with a high disease burden. This systematic review aims to synthesize scientific evidence regarding treatment adherence, emphasizing the influence of family support, healthcare worker involvement, and other contributing factors impacting TB therapy outcomes. A comprehensive literature search was conducted following PRISMA guidelines across four major databases for studies published between 2015 and 2025. Of the 871 identified records, 11 studies met the eligibility criteria and were included for review. The findings revealed that socio-economic status, effective communication between patients and healthcare providers, active family engagement, and adequate health education are significant factors enhancing adherence. Conversely, stigma, adverse drug reactions, poor patient knowledge, and limited healthcare access were commonly identified barriers. Strengthening healthcare infrastructure and implementing family-centered interventions are crucial strategies to improve adherence rates. Furthermore, continuous education and cross-sector collaboration are essential to optimizing TB treatment programs.

Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits any noncommercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if you modified the licensed material. You do not have permission under this license to share adapted material derived from this chapter or parts of it.

Download article (PDF)

<Previous Article In Volume
Next Article In Volume>
Volume Title
Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)
Series
Advances in Health Sciences Research
Publication Date
4 September 2026
ISBN
978-94-6239-762-0
ISSN
2468-5739
DOI
10.2991/978-94-6239-762-0_24How to use a DOI?
Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits any noncommercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if you modified the licensed material. You do not have permission under this license to share adapted material derived from this chapter or parts of it.

Cite this article

risenwbib
TY  - CONF
AU  - Fransiskus Andriyani Djemahu
AU  - Chairun Wiedyaningsih
AU  - Anna Wahyuni Widayanti
PY  - 2026
DA  - 2026/09/04
TI  - Treatment Adherence and Factors Influencing the Success of Tuberculosis Therapy: A Systematic Review
BT  - Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)
PB  - Atlantis Press
SP  - 378
EP  - 394
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6239-762-0_24
DO  - 10.2991/978-94-6239-762-0_24
ID  - Djemahu2026
ER  -