Study on the Delivery of Curcumin Using Corn Zein and Phospholipid Composite Nanoparticles

DOI

10.2991/978-94-6463-829-5_5How to use a DOI?

Keywords

Curcumin; Nanoparticles; Stability; Bioavailability

Abstract

Curcumin has antioxidant, anti-inflammatory, and liver-protective properties. However, its efficacy is limited due to poor stability and low gastrointestinal retention. This study employs corn zein and phospholipid composite nanoparticles as encapsulating materials to improve the stability and bioavailability of curcumin. When the ratio of corn zein to phospholipid is 5:1, the nanoparticles have an average particle size of 180.2 nm and an encapsulation efficiency of 95.8%. The retention rates of curcumin under light and heat conditions are 65.1% and 83.2%, respectively. Additionally, the composite nanoparticles regulate the gastrointestinal digestion and release of curcumin. The corn zein-phospholipid composite nanoparticles can help expand the application range of curcumin and facilitate the development of more curcumin-based products.

Copyright

© 2025 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Yong Cai
PY  - 2025
DA  - 2025/08/28
TI  - Study on the Delivery of Curcumin Using Corn Zein and Phospholipid Composite Nanoparticles
BT  - Proceedings of the 2025 International Conference on Chemical Engineering and Biological Science (CEBS 2025)
PB  - Atlantis Press
SP  - 33
EP  - 42
SN  - 2352-5401
UR  - https://doi.org/10.2991/978-94-6463-829-5_5
DO  - 10.2991/978-94-6463-829-5_5
ID  - Cai2025
ER  -