Proceedings of the 8th International Conference on Neuroscience, Neurology, and Psychiatry 2025 (ICONAP 2025)

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Evidence-Based Case Report: The Role of Methamphetamine in Triggering Schizophrenia in a 15-Year-Old Adolescent

Authors
Vitro Darma Yusra1, Nazli Mahdinasari Nasution1, *, Elmeida Effendy1, *
1Department of Psychiatry, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20155, Sumatera Utara, Indonesia
*Corresponding author. Email: its_nazli@yahoo.com
*Corresponding author.
Corresponding Authors
Nazli Mahdinasari Nasution, Elmeida Effendy
Available Online 25 December 2025.
DOI
10.2991/978-94-6463-966-7_21How to use a DOI?
Keywords
Evidence-Based Case Report; Methamphetamine; Psychosis; Adolescent; Schizophrenia
Abstract

Adolescent methamphetamine (meth) abuse is a serious health problem with long-term neuropsychiatric consequences. Studies show that up to 60% of heavily dependent methamphetamine users experience psychotic symptoms. Previous systematic reviews have also shown that high frequency of use and severity of dependence significantly increase the risk of psychosis, by 3-11-fold and 2-3-fold, respectively. This Article searches were conducted on PubMed®, ProQuest®, and EBSCO®. The screening process was based on eligibility criteria to obtain relevant articles. A case show a 15-year-old male patient with a history of daily methamphetamine use (up to 2 grams/week) developed persistent psychotic symptoms despite abstinence. Symptoms included auditory hallucinations, suspicious ideation, and suicide attempts. Previous studies have also shown a 9.37-fold increased risk of schizophrenia diagnosis in the methamphetamine-using population and a 1.8-fold increased risk of suicide attempts. So Methamphetamine-induced psychosis can progress to Schizophrenia, especially in users with high exposure and heavy dependence. Long-term intervention approaches and comprehensive rehabilitation are essential in the adolescent age group.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 8th International Conference on Neuroscience, Neurology, and Psychiatry 2025 (ICONAP 2025)
Series
Advances in Health Sciences Research
Publication Date
25 December 2025
ISBN
978-94-6463-966-7
ISSN
2468-5739
DOI
10.2991/978-94-6463-966-7_21How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Vitro Darma Yusra
AU  - Nazli Mahdinasari Nasution
AU  - Elmeida Effendy
PY  - 2025
DA  - 2025/12/25
TI  - Evidence-Based Case Report: The Role of Methamphetamine in Triggering Schizophrenia in a 15-Year-Old Adolescent
BT  - Proceedings of the 8th International Conference on Neuroscience, Neurology, and Psychiatry 2025 (ICONAP 2025)
PB  - Atlantis Press
SP  - 136
EP  - 147
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-966-7_21
DO  - 10.2991/978-94-6463-966-7_21
ID  - Yusra2025
ER  -