Proceedings of the 2nd World Conference on Health and Social Sciences (WCHSS 2024)

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The Role of Knowledge and Motivation in Multidrug-Resistant Tuberculosis (MDR-TB) Incidence

Authors
Aan Sutandi1, Martika Hijriani1, Apriana Rahmawati1, *, Harizza Pertiwi1
1Nursing Study Program, Faculty of Nursing and Midwifery, Universitas Binawan, East Jakarta, Indonesia
*Corresponding author. Email: anaapriana.ar@gmail.com
Corresponding Author
Apriana Rahmawati
Available Online 26 June 2025.
DOI
10.2991/978-94-6463-774-8_10How to use a DOI?
Keywords
Drug Resistant Tuberculosis; Knowledge; Motivation
Abstract

Multidrug-resistant tuberculosis (MDR-TB) is defined as tuberculosis caused by Mycobacterium tuberculosis strains resistant to at least isoniazid (INH) and rifampicin (RMP), confirmed through drug sensitivity testing or rapid molecular diagnostics (e.g., GeneXpert). Due to this resistance to first-line anti-tuberculosis medications, MDR-TB necessitates prolonged treatment with second-line drugs. This study aimed to analyze risk factors associated with MDR-TB incidence at a hospital in Bogor, Indonesia. A descriptive-analytical correlational study design with a cross-sectional approach was employed. Participants included 140 purposively sampled MDR-TB patients undergoing treatment for less than 24 months, confirmed by rapid molecular test results. Bivariate analysis using the chi-square test (significance threshold p < 0.05) revealed significant associations between MDR-TB incidence and patient knowledge about the disease (p = 0.044) as well as patient motivation (p = 0.047). These findings underscore the need for healthcare providers managing tuberculosis cases to integrate systematic knowledge assessments at initial diagnosis and continuous motivational support during treatment. Such strategies may reduce the likelihood of drug resistance development.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd World Conference on Health and Social Sciences (WCHSS 2024)
Series
Advances in Health Sciences Research
Publication Date
26 June 2025
ISBN
978-94-6463-774-8
ISSN
2468-5739
DOI
10.2991/978-94-6463-774-8_10How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Aan Sutandi
AU  - Martika Hijriani
AU  - Apriana Rahmawati
AU  - Harizza Pertiwi
PY  - 2025
DA  - 2025/06/26
TI  - The Role of Knowledge and Motivation in Multidrug-Resistant Tuberculosis (MDR-TB) Incidence
BT  - Proceedings of the 2nd World Conference on Health and Social Sciences (WCHSS 2024)
PB  - Atlantis Press
SP  - 96
EP  - 102
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-774-8_10
DO  - 10.2991/978-94-6463-774-8_10
ID  - Sutandi2025
ER  -