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Graft versus host disease (GVHD) of the gut is associated with significant morbidity and mortality after allogeneic hematopoietic cell transplant (allo-HCT). No guidelines exist regarding repeat endoscopy after failure of first-line treatment with steroids. We aimed to study if repeat endoscopic biopsy...

In reality, there are so-called holiday effects in the sales of many consumer goods, and their sales data have the characteristics of double trend change of time series. In view of this, by introducing the seasonal decomposition and ARIMA model, this paper proposes a sales forecasting model for the consumer...

The objective of this study was to describe the overall pattern of morbidity and mortality of children seen at the Thai Binh Paediatric Hospital in Vietnam, with a focus on infectious diseases. A retrospective review of hospitalisation records was conducted from 1 January 2015 to 31 December 2019. Data...

We use an algorithm based on the notion of transvectants from classical invariant theory in determining the form of Stanley decomposition of the ring of invariants for the coupled Takens–Bogdanov systems when the Stanley decompositions of the Jordan blocks of the linear part are known at each stage....

The coronavirus disease 2019 (COVID-19) is a pandemic with a high rate of hospitalization, admission to intensive care units, and mortality. Identifying patients at the highest risk for severe disease is important to facilitate early, aggressive intervention. High red blood cell distribution width (RDW)...

Background: Indicators obtained from the analysis of the radial pulse wave allow an indirect evaluation of the interaction between cardiac ejection and arterial walls. Objectives: To analyze the characteristics of the arterial pulse in young elite athletes through a cross-sectional observational study. Methods:...

African countries have over the years experienced persistent current account deficits. The role of asymmetries in explaining the response of trade balance to exchange rate movement has not received adequate attention as linear models dominate extant empirical literature. In this paper, we examined the...

In this study, we represent an application of the geometrical characterization of μ-prolongations of vector fields to the nonlinear partial differential Gardner equation with variable coefficients. First, μ-symmetries and the corresponding μ-symmetry classification are investigated and then μ-reduction...

Introduction: Comparison of Mobil-O-Graph® with SphygmoCor® exclusively in treatment- naïve hypertensives has never been done. Aims of the study were to assess 1) intra- device agreement between both methods, 2) inter-device agreement between two surface measurements of SC (subtracted distance (cfPWVsub))...

Lower body negative pressure (LBNP) has been used to assess the cardiovascular effect of preload reduction. We are the first to use MRI to investigate ventricular volumes and great vessel flow during LBNP. 13 volunteers (23–47 years) underwent LBNP at 0, −5 and −20mmHg. We acquired contiguous short...

An increasing number of individuals will face age-related cognitive difficulties, as life expectancy has increased globally. It is therefore important to identify modifiable risk factors for cognitive impairment. Very short- to mid-term blood pressure variability (BPV) may be such factor, as it may cause...

Background: To date no definitive results exist about the relationship of Serum Uric Acid (SUA) and TOD in HT subjects. We sought to determine if such an association exist between SUA and subclinical cardiac, vascular and renal alterations in HT. Methods: We enrolled 632 consecutive outpatients, followed...

Platelet activation by thrombin is an auto-amplification loop of thrombin generation, a major factor in the formation of atherosclerotic plaques. The small G protein RhoA, under the direct control of the exchange factor Arhgef1, modulates several cellular functions in inflammation. The objective was...

Background: Matrix metalloproteinase-12 (MMP12) may modulate arterial stiffening with age [1]. We aimed to study the effect of aging on biaxial arterial stiffness in wild-type (WT) and MMP12 knock-out (MMP12-/-) mice. Methods and Results: After euthanasia, descending thoracic (DTA) and suprarenal abdominal...

Purpose/Background/Objectives: Hypertension is associated with several markers of subclinical target organ damage (TOD). Short-term blood pressure variability (SBPV) is a prognostic factor for cardiovascular events in hypertensives. We hypothesised that there is a relationship between SBPV and TOD in...

Purpose/Background/Objectives: Obesity is a well-known risk factor of cardiovascular diseases and a potentially modifiable determinant of arterial ageing. The objectives of this experimental study were to assess the effects of a long-term high fat diet (HFD) on metabolism, adipose tissues and phenotypes...

This paper proposes a knee android model (Knee-AM) that can reproduce the internal-external rotation with screw-home movement (SHM) of the human knee. This rotation of the Knee-AM was realized by changing the number, lengths, and fixing points of the nylon-cords of our previous Knee-AM. Moreover, when...

In Vehicular Ad-hoc Networks, security is a important issue. In the past years, several approaches have been proposed for solving Sybil attack. In this paper a novel scheme to detect the Sybil nodes is presented. The proposed scheme utilizes unmodifiable physical measurements of beacon messages. To increase...

Currently, we are witnessing a growing trend in the study and application of problems in the framework of Big Data. This is mainly due to the great advantages which come from the knowledge extraction from a high volume of information. For this reason, we observe a migration of the standard Data Mining...

In this paper, an adaptive multiple-model controller is developed for nonlinear systems in parametric-strict-feedback form. Unlike the previous results, a switching scheme is not required here to switch the most appropriate model into the controller design. The new scheme reduces the number of identification...

In this paper we discuss the Moyal deformed 2D Euler flows and its Lax pairs. This in turn yields the semi-discrete version of 2D Euler equation.

We review the construction of Lax pairs with spectral parameter for twisted and utwisted elliptic Calogero-Moser systems defined by a general simple Lie algebra G, and the corresponding solution of N = 2 SUSY G Yang-Mills theories with a hypermultplet in the adjoint representation of G.

We consider the variational symmetry from the viewpoint of the non-integrability criterion towards dynamical systems. That variational symmetry can reduce complexity in determining non-integrability of general dynamical systems is illustrated here by a new non-integrability result about Hamiltonian systems...

Noether’s theorem is used to determine first integrals admitted by a generalised Lane-Emden equation of the second kind modelling a thermal explosion. These first integrals exist for rectangular and cylindrical geometry. For rectangular geometry the first integrals show the symmetry of the temperature...

The proposed relational fuzzy clustering method, called FRFP ( fuzzy relational fixed point), is based on determining a fixed point of a function of the desired membership matrix. The ethod is compared to other relational clustering methods. Simulations show the method to be very effective and less computationally...

The hazard risk and disaster degree of damage was confirmed about the forest and grassland fire in Inner Mongolia by the occurrence rule of fires, distribution of high temperature points, characteristic of distribution of vegetation types, and the extent of road coverage. Production of risk assessment...

Background: Ischemic stroke is an important cause of death and disability. However, data about gender-differences in stroke are controversial. Methods: In the nationwide sample, male and female inpatients were selected by screening for ischemic stroke by ICD-Code(I63) and compared. In a second study,...

Data-driven control has been proposed for directly calculating control parameters using experimental data. Specifically, the Virtual Reference Feedback Tuning (VRFT) has been proposed for linear time-invariant systems. In the field of machine learning, the ensemble learning was proposed to improve the...

In this article we derive the triangular representations of the fundamental eigensolutions of the focusing 1 + 1 AKNS system with symmetric nonvanishing boundary conditions. Its continuous spectrum equals 𝕉∪[-iμ,iμ] , where μ is the absolute value of the AKNS solution at spatial infinity. We...

Remdesivir is a broad spectrum antiviral agent meant to inhibit viral RNA polymerases against members of several virus families, including filoviruses. Although reported for significant clinical improvements in COVID-19, a detailed observation of the connection with the drawbacks of remdesivir therapy...

Every distributed system requires a secure environment for its users. Security becomes even more important if users exchange sensitive information and value, across the network. An e-commerce environment is an example of a distributed system in which security is of a high priority. It is important that...

Objectives: Sex differences for parameters of arterial wave reflection and arterial stiffness were reported from single office measurements, but circadian patterns were not extensively investigated up to now. The aim of this study was to determine sex differences between day and night values of ambulatory...

Objective: This study examines effects of high salt diet on arterial blood pressure and aortic function in rats. Methods: Sprague-Dawley rats were fed either high salt content chow or normal chow from weaning. Weight, tail-cuff systolic blood pressure (SBP), water and food intake, and urine output were...

Introduction: The PORT-VASPh Cohort was designed to contribute to a better understanding of vascular function in children and adolescents, mostly focusing PWV and other complementary aspects of arterial hemodynamics. Methods: The PORT-VASPh cohort is a prospective and observational study, with 953 children...

Background/Objectives: Tetrahydrobiopterin (BH4) is a cofactor for nitric oxide synthase (NOS). Oxidative stress, reported in black populations (1), may lead to the oxidation of BH4, the uncoupling of eNOS, decreased NO and increased superoxide levels (2,3). We compared BH4 and markers of oxidative stress...

Background: SNPs on chromosome 9p21.3 risk locus have been associated with cardiovascular diseases. We have established a direct mechanistic link between 9p21 noncoding risk interval and susceptibility to aneurysm in a mouse model with a targeted deletion of the 9p21 noncoding cardiovascular disease...

Background: Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory vascular disease involving medium-sized muscular arteries, whose pathophysiology is still unknown. Objectives: We aimed at identifying systemic vascular alterations in usually non-affected arteries of patients with...

Background: Hyperuricemia is common in patients with hypertension, diabetes and obesity. Whether it is an independent cardiovascular risk factor (CVRF) or not remains controversial. Purpose: To determine the prognostic value of uricemia in the setting of acute coronary syndrome (ACS). Methods: Retrospective...

Background: We tested the association between birthweight and arterial stiffness measured by aortic pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI) in a birth cohort of 30 year old Jamaicans. Methods: Participants were from the 1986 Jamaica Birth Cohort. Arterial stiffness was measured...

Obesity is associated with diabetes and an increased cardiovascular risk. Leptin-deficient mice (ob/ob) are used as model of metabolic disease: they are characterized by obesity and insulin-resistance. Aim of this work is to identify early cardiovascular alterations in young ob/ob mice using micro-ultrasound...

Background: Aortic root dilation and type A aortic dissection are the most common cardiovascular complications of Marfan syndrome (MFS). Current clinical management of MFS patients relies on a close follow-up of aortic root diameter and preventive aortic root surgery in case of severe or fast-progressing...