Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)

6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)

📍Yogyakarta, Indonesia🗓️ 30-31 July 2025
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Antibiotic Consumption for Pneumonia Treatment: A Systematic Review of Trends in Indonesia and Other Countries

Authors
Dina Cory Belinda Leiwakabessy1, Dwi Endarti2, *, Tri Murti Andayani3
1Master Program In Pharmacy Management, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
2Departemen of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
3Departemen of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
*Corresponding author. Email: endarti_apt@umg.ac.id
Corresponding Author
Dwi Endarti
Available Online 4 September 2026.
DOI
10.2991/978-94-6239-762-0_22How to use a DOI?
Keywords
ATC; DDD; Evaluation; Antibiotic Consumption; Pneumonia
Abstract

One of the infectious diseases that is of particular concern in Indonesia is pneumonia. The trend in antibiotic use among pneumonia patients in long-term care facilities, as reported by Chae et al. in the Republic of Korea, shows an increase in both the number of pneumonia cases and antibiotic consumption. The WHO AWaRe system categorizes antibiotics, revealing a shift in prescribing patterns towards broad-spectrum antibiotics, which could potentially worsen microbial resistance. This systematic review aims to evaluate the use of antibiotics in hospitalized pneumonia patients in hospitals in Indonesia and other countries in addressing the issue of antibiotic resistance over the past 10 years. Inclusion criteria included studies on antibiotic use using the ATC/DDD method in pneumonia. Antibiotic consumption in Indonesia (24.51–185.36 DDD/100 patient-days) was higher compared to South Korea (15.5–18.67 DDD) and Hungary (11.41 DDD). Broad-spectrum antibiotics (ceftriaxone, levofloxacin, and meropenem) dominated, with the DU90% segment showing >50% use of antibiotics in the “Watch” category. The high consumption was influenced by non-compliant clinical practices, excessive empirical use, and low public awareness. There is a need to improve adherence to pneumonia management guidelines, closely monitor antibiotic use, and educate healthcare workers and the community to reduce AMR.

Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits any noncommercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if you modified the licensed material. You do not have permission under this license to share adapted material derived from this chapter or parts of it.

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Volume Title
Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)
Series
Advances in Health Sciences Research
Publication Date
4 September 2026
ISBN
978-94-6239-762-0
ISSN
2468-5739
DOI
10.2991/978-94-6239-762-0_22How to use a DOI?
Copyright
© 2026 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits any noncommercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if you modified the licensed material. You do not have permission under this license to share adapted material derived from this chapter or parts of it.

Cite this article

risenwbib
TY  - CONF
AU  - Dina Cory Belinda Leiwakabessy
AU  - Dwi Endarti
AU  - Tri Murti Andayani
PY  - 2026
DA  - 2026/09/04
TI  - Antibiotic Consumption for Pneumonia Treatment: A Systematic Review of Trends in Indonesia and Other Countries
BT  - Proceedings of the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BIOMIC 2025)
PB  - Atlantis Press
SP  - 350
EP  - 361
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6239-762-0_22
DO  - 10.2991/978-94-6239-762-0_22
ID  - Leiwakabessy2026
ER  -