Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)

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The Effectiveness of Lemongrass (Cymbopogon Citratus L.) Extract Nanoemulsion on Reducing NAFLD Scores and Necrosis Levels in the Liver of Type 2 Diabetes Mellitus Rats After Streptozotocin Induction

Authors
Poppy Marzuki1, *, Chrismis Novalinda Ginting1, Linda Chiuman1, Anggi Aprilyani1
1Department of Biomedical Science, Faculty of Medicine, Dentistry, and Health Science, Universitas Prima Indonesia, Medan, Indonesia
*Corresponding author. Email: poppymarzuki12@gmail.com
Corresponding Author
Poppy Marzuki
Available Online 2 January 2026.
DOI
10.2991/978-94-6463-962-9_14How to use a DOI?
Keywords
Lemongrass; Nanoemulsion; Liver; Nafld; Diabetes
Abstract

The liver is a vital organ in the body that plays a role in the metabolism of toxic substances. Type 2 diabetes mellitus increases the risk of microvascular (retinopathy, neuropathy, and nephropathy) and macrovascular (cardiovascular) complications. This study aims to examineeffectiveness of lemongrass extract nanoemulsion (Cymbopogon Citratus L.) on reducing NAFLD scores and necrosis levels in the liver of type 2 diabetes mellitus mice after streptozoticin induction with a research sample of 20 Wistar strain rats were divided into 5 groups, namely positive control group, negative control group, treatment group 1, 2 and 3. With the resultsgivingnanoemulsion of lemongrass extract(Cymbopogon Citratus L) can also reduce blood glucose levels in mice with the effectiveness of the extract at concentrations of 3%, 2% and then 1%.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
Series
Advances in Health Sciences Research
Publication Date
2 January 2026
ISBN
978-94-6463-962-9
ISSN
2468-5739
DOI
10.2991/978-94-6463-962-9_14How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Poppy Marzuki
AU  - Chrismis Novalinda Ginting
AU  - Linda Chiuman
AU  - Anggi Aprilyani
PY  - 2026
DA  - 2026/01/02
TI  - The Effectiveness of Lemongrass (Cymbopogon Citratus L.) Extract Nanoemulsion on Reducing NAFLD Scores and Necrosis Levels in the Liver of Type 2 Diabetes Mellitus Rats After Streptozotocin Induction
BT  - Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
PB  - Atlantis Press
SP  - 129
EP  - 139
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-962-9_14
DO  - 10.2991/978-94-6463-962-9_14
ID  - Marzuki2026
ER  -