Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)

Analysis of Phytochemical Compounds and Antibacterial Effects of Etlingera elatior Fruit Extract on Staphylococcus aureus

Authors
Chrismas Gideon Bangun1, Gusbakti Rusip2, *, Maya Sari Mutia3
1Doctoral Program, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
2Department of Family Medicine, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
3Deparment of Histology, Faculty of Medicine, Universitas Prima Indonesia, Medan, Indonesia
*Corresponding author. Email: gusrusip@gmail.com
Corresponding Author
Gusbakti Rusip
Available Online 2 January 2026.
DOI
10.2991/978-94-6463-962-9_19How to use a DOI?
Keywords
Etlingera elatior; phytochemical; antibacterial; Staphylococcus aureus
Abstract

Etlingera elatior a tropical plant commonly found in Indonesia, is traditionally used for its medicinal properties. However, limited studies have explored its bioactive content and antibacterial effects. This study aimed to identify the phytochemical constituents and evaluate the antibacterial activity of E. elatior fruit extract against Staphylococcus aureus. The fruit of E. elatior was collected from Pancur batu, Deli Serdang Regency, and subjected to hydroethanolic maceration. Phytochemical screening was conducted using standard qualitative methods to detect the presence of alkaloids, flavonoids, tannins, terpenoids, saponins, and phenolics. Antibacterial activity was assessed using the Kirby-Bauer disc diffusion method against S. aureus. Extract concentrations ranging from 0.078125% to 50% were tested, with chloramphenicol as the positive control and DMSO as the negative control. Zones of inhibition were measured and analyzed in triplicate. Phytochemical analysis revealed the presence of alkaloids, flavonoids, tannins, terpenoids, and phenolics, while saponins were absent. The extract demonstrated a concentration-dependent antibacterial effect, with the highest inhibition zone observed at 50% concentration (12.8 ± 1.52mm). No activity was recorded below 0.3125%. The positive control showed a significant inhibition zone (23.56 ± 2.43 mm), whereas the negative control showed none. The hydroethanolic extract of E. elatior fruit contains multiple bioactive compounds and exhibits notable antibacterial activity against S. aureus. These findings support its potential as a natural antibacterial agent and warrant further investigation into its therapeutic applications

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
Series
Advances in Health Sciences Research
Publication Date
2 January 2026
ISBN
978-94-6463-962-9
ISSN
2468-5739
DOI
10.2991/978-94-6463-962-9_19How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Chrismas Gideon Bangun
AU  - Gusbakti Rusip
AU  - Maya Sari Mutia
PY  - 2026
DA  - 2026/01/02
TI  - Analysis of Phytochemical Compounds and Antibacterial Effects of Etlingera elatior Fruit Extract on Staphylococcus aureus
BT  - Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
PB  - Atlantis Press
SP  - 196
EP  - 204
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-962-9_19
DO  - 10.2991/978-94-6463-962-9_19
ID  - Bangun2026
ER  -