Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)

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Lancing Leaves (Solanum mauritianum Scop.) as a Potential Herbal Antidiabetic Agent: A Review of Ethnobotany, Pharmacology, and Experimental Evidence

Authors
Vincent Kandiawan1, Fiska Maya Wardhani2, Refi Ikhtiari3, *
1Department of Biomedical Science, Faculty of Medicine, Dentistry, and Health Science, Universitas Prima Indonesia, Medan, Indonesia
2Faculty of Medicine, Universitas Pendidikan Indonesia, Bandung, Indonesia
3Department of Biomedical Science, Faculty of Medicine, Dentistry, and Health Science, Universitas Prima Indonesia, Medan, Indonesia
*Corresponding author. Email: refiikhtiari@unprimdn.ac.id
Corresponding Author
Refi Ikhtiari
Available Online 2 January 2026.
DOI
10.2991/978-94-6463-962-9_9How to use a DOI?
Keywords
Solanum mauritianum; lancing leaves; diabetes mellitus; antioxidants; ethnopharmacology; β $$\beta $$-cell; oxidative stress
Abstract

The increasing prevalence of type 2 diabetes mellitus (T2DM) highlights the need for safer, more accessible treatment alternatives beyond current pharmacotherapies, which often cause adverse effects. Plant-based interventions rooted in ethnopharmacological traditions have gained traction. Solanum mauritianum Scop., locally known as "lancing," is a plant traditionally used by the Karo people of North Sumatra. Recent experimental data suggest its strong antioxidant and antidiabetic activity. This review synthesizes current literature on the phytochemical profile, ethnomedicinal usage, and antidiabetic potential of S. mauritianum, emphasizing its effects on blood glucose regulation, oxidative stress mitigation, and β -cell protection. Findings suggest promising pharmacological activity, particularly at higher extract doses (750 mg/kg), with efficacy approaching that of metformin in animal models. However, further studies are needed, especially clinical trials, to validate its efficacy and safety in humans.

Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
Series
Advances in Health Sciences Research
Publication Date
2 January 2026
ISBN
978-94-6463-962-9
ISSN
2468-5739
DOI
10.2991/978-94-6463-962-9_9How to use a DOI?
Copyright
© 2025 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Vincent Kandiawan
AU  - Fiska Maya Wardhani
AU  - Refi Ikhtiari
PY  - 2026
DA  - 2026/01/02
TI  - Lancing Leaves (Solanum mauritianum Scop.) as a Potential Herbal Antidiabetic Agent: A Review of Ethnobotany, Pharmacology, and Experimental Evidence
BT  - Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
PB  - Atlantis Press
SP  - 77
EP  - 86
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-962-9_9
DO  - 10.2991/978-94-6463-962-9_9
ID  - Kandiawan2026
ER  -