Application of Wet Granulation Method in the Tablet Formulation of Ethanol Extract of Tetanus Leaf (Leea aequata L.) with Muscilago Amyli as a Binder

DOI

10.2991/978-94-6463-962-9_33How to use a DOI?

Keywords

Traditional medicines; Titanus leaf; Granulation; Tablets

Abstract

Currently, degenarative disease are a major in Indonesia, affecting approximately thirty percent of the population. As an alternative treatment, Indonesia communities tend to Prefer herbal or traditional medicines. One widely used plant is Titanus leaf (Leea aequata L.) using the wet granulation method. Extractiion was carried out using ninety six percent ethanol, as the leaves are know to contain active compounds such as flavanoids, phenols, tannins, quinones, saponins, alkaloid, and steroids or terpenoids. The study specifically compares the use of mucilago amyli as a binder in three different formulation. Formulation 1 twenty percent, Formulation 2 ten percent, and Formulation 3 five percent and then to determine the concentration that produces high quality tablet meeting required standarts. Based on the test results, Formuation one, which uses twenty the most acceptable tablets.

Copyright

© 2025 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Astriani Natalia Br Ginting
AU  - Roy Indrianto Bangar
AU  - Fanny Margaretha Br Colia
AU  - Wulan Seppia Ningsih
PY  - 2026
DA  - 2026/01/02
TI  - Application of Wet Granulation Method in the Tablet Formulation of Ethanol Extract of Tetanus Leaf (Leea aequata L.) with Muscilago Amyli as a Binder
BT  - Proceedings of the 2nd International Conference on Lifestyle Diseases and Natural Medicine (ICOLIFEMED 2025)
PB  - Atlantis Press
SP  - 336
EP  - 346
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-962-9_33
DO  - 10.2991/978-94-6463-962-9_33
ID  - Ginting2026
ER  -