Welcome to the Proceedings of the E-Learning and Smart Engineering Systems (ELSES 2025). The 2025 edition of ELSES was organized under the theme “Reinventing online learning: the alliance of artificial intelligence, technological sciences, humanities, and communication for an innovative and inclusive education.” This theme highlights the importance of integrating multiple disciplines to rethink and transform digital learning environments through intelligent technologies, enriched cultural and scientific content, and multidimensional pedagogical approaches.

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