All of the articles in this proceedings volume have been presented at the 6th International Conference on Bioinformatics, Biotechnology, and Biomedical Engineering (BioMIC 2025) during 30–31 July 2025 in Yogyakarta, Indonesia. These articles have been peer reviewed by the members of the Scientific Committee...

Willingness to pay (WTP) for the human papillomavirus (HPV) vaccine is an important indicator of public acceptance and affordability related to cervical cancer prevention efforts. This systematic review aimed to examine the range of WTP values and explore the associated determinants of WTP for the HPV...

Human Papillomavirus (HPV) vaccination is a proven preventive strategy against cervical cancer, yet affordability and acceptance remain challenges, particularly in low- and middle-income countries (LMICs). This systematic review compares willingness to pay (WTP) for HPV vaccines between LMICs and high-income...

Understanding the meaning of willingness to pay (WTP) for cancer screening in Asia Continent is essential for improving accessibility and participation in early detection programs. This systematic review synthesizes existing evidence on the key factors influencing WTP. This review provides comprehensive...

Heart failure with reduced ejection fraction (HFrEF) is a major global health and economic challenge. Sacubitril/valsartan, an angiotensin receptor-neprilysin inhibitor (ARNI), has demonstrated superior clinical efficacy compared to enalapril, but its cost-effectiveness across different economic settings...

This article investigates the interplay between data privacy, Big Data, and public health within the framework of Indonesian legislation, specifically focusing on the implications of the Health Law and the Personal Data Protection Law. This analysis elucidates the paramount importance of managing patient...

Measuring health-related quality of life (HRQOL) in children is essential for evaluating the impact of illness and treatment beyond clinical outcomes. This systematic review aims to identify HRQOL instruments used in Indonesia pediatric populations and assess their validation status. Following PRISMA2020...

Maternal and post-neonatal mortality remain persistent and pressing public health issues in East Java, Indonesia, reflecting ongoing inequalities in healthcare delivery and policy implementation. Traditional count regression models often struggle to address overdispersion and tend to ignore geographic...

Indragiri Hilir Regency is one of twelve districts/cities in Riau Province and is also one of the districts with the largest population. With a relatively large population, it makes its demographic unique, both in terms of fertility indicators, mortality indicators and migration indicators. One of the...

Maternal mortality remains a significant public health issue in Indonesia, with wide disparities across provinces. While national strategies have focused on expanding health insurance coverage and increasing the number of skilled birth attendants, the role of infrastructure, particularly road conditions,...

Cardiovascular disease (CVD) causes one-third of deaths in Indonesia. Utilisation of the Indonesian National Health Insurance Scheme (JKN) to cover CVD is increasing. Reducing CVD costs in hospitals requires appropriate interventions. This study aims to evaluate the potential cost savings for patients...

Introduction Patient satisfaction is a key indicator of healthcare quality, reflecting how well care meets patients’ needs and expectations. Positive patient experiences improve health outcomes, treatment adherence, and healthcare utilization. Satisfaction data help identify factors to...

Patient satisfaction is a key indicator of hospital service quality. Outpatient pharmacy services support medication access, clear communication, and adherence. Variations in satisfaction across countries emphasize the need for structured evaluation to identify service gaps and improve pharmacy care....

Effective topical drug delivery systems pose a significant challenge in dermatological therapy, particularly in overcoming physiological barriers such as stratum corneum penetration, ensuring drug stability, and preventing uncontrolled release. Chitosan–sodium tripolyphosphate (TPP)-based nanoparticles...

Efficient dissociation of retinal cells requires careful selection of proteases to preserve surface epitopes critical for downstream analyses. This study aimed to identify the most suitable protease for murine retina dissociation without compromising key surface markers. Retinas were harvested from normal...

The retinal tissue consists of many cell types with distinct characteristics and functions. Many eye diseases are initiated by a dysregulated retinal cell subtype within the tissue. A feasible method is needed for single-cell transcriptomic studies. It is possible to enrich retinal cell subtypes by combining...

Deoxyribonucleic acid (DNA) extraction is the process of isolating DNA from cells or tissues of living organisms for further analysis. DNA extraction must be performed in matrix analysis of a sample to identify nucleic acids. This study evaluated the effectiveness of ultrasound in extracting pig DNA,...

Accurate forecasting of pharmaceutical demand is critical for healthcare sustainability, yet it faces persistent challenges stemming from data limitations and contextual complexities. This review synthesizes evidence from 12 studies (2018–2023) identified through systematic searches of Scopus, Web of...

Background Good Distribution Practices (GDP) are essential for maintaining the quality and safety of pharmaceutical products throughout the distribution chain. However, levels of compliance among pharmaceutical wholesalers (PBFs) in Indonesia vary considerably. Objectives: This review...

Efficient drug management is essential to ensuring hospital-quality, affordability, and rational use of medicines. In Indonesia, the Ministry of Health has established national indicators through Regulation to evaluate the quality of drug selection and procurement.This systematic review aims to assess...

Proton pump inhibitors (PPIs) are among the most widely utilized medications globally. Their use in elderly individuals is recommended for the management of gastrointestinal disorders, as well as for prophylactic purposes to mitigate adverse effects associated with certain medications. The prevalence...

One of the infectious diseases that is of particular concern in Indonesia is pneumonia. The trend in antibiotic use among pneumonia patients in long-term care facilities, as reported by Chae et al. in the Republic of Korea, shows an increase in both the number of pneumonia cases and antibiotic consumption....

This study analyzed factors associated with delayed treatment initiation among patients with drug-sensitive tuberculosis (TB) in South Sulawesi, Indonesia. A retrospective observational study was conducted using medical records of drug-sensitive TB patients registered between January and December 2023...

Tuberculosis (TB) remains a major public health challenge worldwide, with treatment adherence playing a critical role in determining therapeutic success. However, non-adherence to TB medication remains a persistent obstacle, particularly in countries with a high disease burden. This systematic review...

Medication adherence and limited patient knowledge remain significant barriers to the effective management of hypertension. Telepharmacy defined as pharmacist led remote care has demonstrated promising potential in addressing these challenges. This study aimed to systematically review and meta-analyze...

Electronic prescribing (EP) is a key innovation in improving the efficiency and safety of healthcare services. However, its implementation in healthcare facilities still faces various challenges. Therefore, it is crucial to evaluate healthcare professionals’ perceptions of EP to assess its effective...

The advancement of digital health technologies has influenced various aspects of healthcare, including the adoption of electronic prescribing (e-prescribing) systems. E-prescribing is designed to reduce prescription errors, streamline processes, and improve satisfaction among healthcare providers and...

The usability evaluation of digital pharmacy information systems is crucial for their successful adoption and sustained use in healthcare settings. Although previous systematic reviews have addressed this topic, gaps remain in understanding the influence of recent developments, including e-prescribing...

Drug interactions are a major concern in clinical therapy due to their potential to affect both efficacy and safety. Medications with a narrow therapeutic index, such as digoxin and warfarin, are especially susceptible. With rapid advancements in technology, generative AI platforms like ChatGPT-4o mini,...

Psoriasis is a chronic autoimmune disease affecting approximately 3% of the global population, with no effective long-term treatment options. This study uses the FAERS database, network pharmacology, and molecular docking to investigate drug repurposing for psoriasis. The FAERS analysis identified ranitidine...

Cancer continues to pose a considerable global health challenge, as traditional therapies such as chemotherapy and radiotherapy are frequently constrained by drug resistance and detrimental side effects. Natural compounds such as chalcones have attracted interest for their potential as anticancer agents...

Delayed-onset muscle soreness (DOMS) is a condition that occurs after exercise and is characterized by muscle pain, stiffness, and decreased functionality. Traditional therapies such as NSAIDs often have limitations owing to their adverse effects and variable effectiveness. This study aimed to investigate...

Pathological bleeding presents a significant clinical challenge due to limited effective anti-hemorrhagic therapies. Varespladib, originally developed as an anti-inflammatory agent has shown potential as a repurposed anti-hemorrhagic drug. Our study aimed to explore varespladib’s coagulation-modulating...